Document Detail

Parent-offspring resemblance of palmar and plantar dermatoglyphic patterns in Down syndrome.
MedLine Citation:
PMID:  11173849     Owner:  NLM     Status:  MEDLINE    
With the aim of investigating the influence of trisomy 21 on the expression of heritable morphological features, we recorded the palmar and plantar dermatoglyphic patterns in 48 children with Down syndrome (DS), in both their parents, and, as a control, in 57 of their siblings. Using the Kendall tau rank correlation test, a considerable parental influence on the frequency of true patterns in the interdigital areas (IDA) III and IV of the palms (P = 0.3%) and soles (P = 1.0% and 3.8%, respectively) is demonstrated for the control siblings. In the children with DS, this influence is discernible as well, although with no statistical significance. A greater number of families may be required to settle the question.
U Langenbeck; G Herzberger; S Kümmerle
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Cytogenetics and cell genetics     Volume:  91     ISSN:  0301-0171     ISO Abbreviation:  Cytogenet. Cell Genet.     Publication Date:  2000  
Date Detail:
Created Date:  2001-02-22     Completed Date:  2001-03-29     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0367735     Medline TA:  Cytogenet Cell Genet     Country:  Switzerland    
Other Details:
Languages:  eng     Pagination:  157-9     Citation Subset:  IM    
Copyright Information:
Copyright 2001 S. Karger AG, Basel
Institute of Human Genetics, University Hospital, Frankfurt/Main , Germany.
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MeSH Terms
Down Syndrome / genetics,  physiopathology*
Foot Deformities, Congenital / genetics,  physiopathology*
Genetic Predisposition to Disease
Hand Deformities, Congenital / genetics,  physiopathology*
Nuclear Family
Sample Size
Statistics as Topic

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