| Parenchymal and pleural findings in pulmonary embolism visualized by multi-channel detector computed tomography. | |
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MedLine Citation:
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PMID: 20707661 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: A normal computed tomography (CT) scan of the pulmonary arteries in the presence of parenchymal and pleural abnormalities may indicate a false-negative diagnosis of pulmonary embolism (PE). Multi-channel detector CT (MDCT) with thinner collimation may improve the detection of small peripheral PEs causing such abnormalities. PURPOSE: To investigate parenchymal and pleural findings visualized by contrast-enhanced MDCT in patients with and without PE, and to identify possible predictors of PE. MATERIAL AND METHODS: 129 patients with clinical signs of PE were included. In all patients an iopromide-enhanced 64-MDCT (64x0.625 mm collimation, pitch 1.375, overlapping reconstruction with a slice thickness of 0.625 mm, increment of overlapping slice reconstruction 0.43) was performed within 24 h after the onset of the symptoms. RESULTS: MDCT detected PE in 45 of the 129 patients (35%). PE and parenchymal/pleural findings were localized predominantly within the lower lobes. Wedge-shaped opacities were significantly associated with PE (OR =3.00; 95% confidence interval 1.13-7.91). Vascular signs were only visualized in patients with PE. Nodules, consolidations, atelectasis, or effusions were not predictive of PE. CONCLUSION: The present MDCT study verified that parenchymal and pleural findings can be found in patients with or without PE. Wedge-shaped opacities and vascular signs were significantly associated with PE and therefore can be potential predictors of PE. |
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Authors:
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Alexander Pfeil; Peter Schmidt; Regina Hermann; Joachim Böttcher; Gunter Wolf; Andreas Hansch |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Acta radiologica (Stockholm, Sweden : 1987) Volume: 51 ISSN: 1600-0455 ISO Abbreviation: Acta Radiol Publication Date: 2010 Sep |
Date Detail:
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Created Date: 2010-08-16 Completed Date: 2010-09-14 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8706123 Medline TA: Acta Radiol Country: England |
Other Details:
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Languages: eng Pagination: 775-81 Citation Subset: IM |
Affiliation:
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Department of Internal Medicine III, Friedrich-Schiller-University Jena, Germany. alexander.pfeil@med.uni-jena.de |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Aged Aged, 80 and over Contrast Media / administration & dosage False Negative Reactions Female Humans Iohexol / administration & dosage, analogs & derivatives Logistic Models Male Middle Aged Pleura / pathology, radiography* Pulmonary Artery / radiography Pulmonary Embolism / pathology, radiography* Radiographic Image Interpretation, Computer-Assisted Tomography, X-Ray Computed / methods* |
| Chemical | |
Reg. No./Substance:
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0/Contrast Media; 66108-95-0/Iohexol; 73334-07-3/iopromide |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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