| Parathyroid hormone-mediated incorporation of 32P-orthophosphate into phosphatidic acid and phosphatidylinositol in renal cortical slices. | |
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MedLine Citation:
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PMID: 188626 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Parathyroid hormone increased the incorporation of Na2H32PO4 into phosphatidic acid and phosphatidylinositol in cat renal cortical slices. Incorporation was not observed into any other phospholipid. The effects were seen as early as one minute for phosphatidic acid and ten minutes for phosphatidylinositol. 8-Bromoadnosine 3',5'-monophosphate did not mimic the effects of parathyroid hormone. Concentrations of parathyroid hormone, 1 x 10(-8)M to 1 x 10(-7)M, which increased the incorporation of 32p into phosphatidic acid and phosphatidylinositol maximally, did not alter tissue cyclic AMP levels suggesting that the incorporation of 32p was independent of cyclic AMP. |
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Authors:
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H Lo; D C Lehotay; D Katz; G S Levey |
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Publication Detail:
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Type: Journal Article; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
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Title: Endocrine research communications Volume: 3 ISSN: 0093-6391 ISO Abbreviation: Endocr Res Commun Publication Date: 1976 |
Date Detail:
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Created Date: 1977-03-31 Completed Date: 1977-03-31 Revised Date: 2009-10-27 |
Medline Journal Info:
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Nlm Unique ID: 0426337 Medline TA: Endocr Res Commun Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 377-85 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Cats Cyclic AMP / analogs & derivatives, metabolism, pharmacology Dose-Response Relationship, Drug Kidney Cortex / metabolism* Organ Specificity / drug effects Parathyroid Hormone / pharmacology* Phosphates / metabolism* Phosphatidic Acids / biosynthesis* Phosphatidylinositols / biosynthesis* Phosphorus Radioisotopes Time Factors |
| Chemical | |
Reg. No./Substance:
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0/Parathyroid Hormone; 0/Phosphates; 0/Phosphatidic Acids; 0/Phosphatidylinositols; 0/Phosphorus Radioisotopes; 60-92-4/Cyclic AMP |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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