Document Detail

Parathyroid adenoma presenting as tetraparesia.
MedLine Citation:
PMID:  20802446     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: Parathyroid adenomas (PA) are benign tumors. We report an unusual case of delayed diagnosis of a PA and concomitant Vitamin D deficiency presenting as tetraparesia.
METHODS: A 30-year-woman was admitted to our clinic with an inability to walk. Our examination revealed tetraparesia and common, severe muscular atrophy.
RESULTS: Laboratory investigations showed the following: creatinine phosphokinase (CK): 37 IU/L (15-130), calcium (Ca): 11.5 mg/dL (9-11), phosphorus (P): 1.5 mg/dL (2.5-5), parathyroid hormone (PTH): 736.1 pq/mL (15-65), 25-hydroxyvitamin D (25-OHvit D): 4 ng/mL (11-43), and alkaline phosphatase (ALP): 1029.5 lU (64-300). Parathyroid scintigraphy revealed PA. A year after Vitamin D replacement, the patient's neurological status and laboratory findings improved.
CONCLUSION: We suggest that the physicians always keep in mind the primary hyperparathyroidism (HPT) and concomitant Vitamin D deficiency in the differential diagnosis of hypercalcemia when facing atypical neurological symptoms such as tetraparesia.
Asuman Orhan Varoglu; Asude Aksoy; Erhan Varoglu
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Neuro endocrinology letters     Volume:  31     ISSN:  0172-780X     ISO Abbreviation:  Neuro Endocrinol. Lett.     Publication Date:  2010  
Date Detail:
Created Date:  2010-11-01     Completed Date:  2010-12-07     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8008373     Medline TA:  Neuro Endocrinol Lett     Country:  Sweden    
Other Details:
Languages:  eng     Pagination:  451-3     Citation Subset:  IM    
Department of Neurology, Medical Faculty, Ataturk University, Erzurum, Turkey.
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MeSH Terms
Adenoma / complications*
Parathyroid Neoplasms / complications*
Quadriplegia / etiology*
Treatment Outcome
Vitamin D / therapeutic use
Vitamin D Deficiency / complications*,  drug therapy
Reg. No./Substance:
1406-16-2/Vitamin D

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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