Document Detail

Parathyroid adenocarcinoma.
MedLine Citation:
PMID:  2666678     Owner:  NLM     Status:  MEDLINE    
Parathyroid adenocarcinoma is a very rare carcinoma with an equal male-female incidence. The clinical picture that adenocarcinoma of the parathyroid presents is the same as that of hyperparathyroidism due to adenoma. Onset of parathyroid adenocarcinoma occurs primarily in the fourth decade of life. It is not incompatible with long-term survival provided that the entire gland is removed at the initial operation without rupture of the capsule. If the carcinoma recurs, it grows slowly and any spread tends to be local. Distant metastasis is rare. Calcium levels above 13 mg/100 mL should alert the clinician to the possibility of adenocarcinoma of the parathyroid. Increased mitotic figures, increased fibrosis of the gland, and invasion of the vessels and surrounding tissues are the features indicative of malignancy. A review of the literature reveals that fewer than 150 cases of this entity have been reported. The authors present two case reports and discuss the epidemiology, clinical picture, pathology, and therapy of parathyroid adenocarcinoma.
A Nazem; B Anderson; L D Leffal; M Reghini; J Brown
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Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  Journal of the National Medical Association     Volume:  81     ISSN:  0027-9684     ISO Abbreviation:  J Natl Med Assoc     Publication Date:  1989 Jul 
Date Detail:
Created Date:  1989-09-06     Completed Date:  1989-09-06     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  7503090     Medline TA:  J Natl Med Assoc     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  785-9     Citation Subset:  IM    
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MeSH Terms
Middle Aged
Parathyroid Neoplasms*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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