Document Detail

Parathyrin (parathyroid hormone): metabolism and methods for assay.
MedLine Citation:
PMID:  3512127     Owner:  NLM     Status:  MEDLINE    
Parathyrin (parathyroid hormone) radioimmunoassay is a commonly ordered endocrine assay. I discuss here of the metabolism of the hormone and the effect information on this metabolism has had on the development of radioimmunoassays for parathyrin. Although radioimmunoassay is the most widely accepted technique for the routine assay for parathyrin, "high-performance" liquid chromatography, cytochemical bioassay, and homologous bioassay have also been developed for this analyte. Accordingly, I briefly review the clinical utility of these assays in terms of their ability to assess the functional activity of the parathyroid gland.
E K Armitage
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Clinical chemistry     Volume:  32     ISSN:  0009-9147     ISO Abbreviation:  Clin. Chem.     Publication Date:  1986 Mar 
Date Detail:
Created Date:  1986-04-03     Completed Date:  1986-04-03     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  9421549     Medline TA:  Clin Chem     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  418-24     Citation Subset:  IM    
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MeSH Terms
Biological Assay
Calcium / blood
Chromatography, High Pressure Liquid
Hypercalcemia / etiology
Hypocalcemia / metabolism
Metabolic Clearance Rate
Parathyroid Glands / metabolism
Parathyroid Hormone / analysis*,  metabolism,  physiology
Peptide Fragments / analysis,  metabolism,  physiology
Peptide Hydrolases / metabolism
Reg. No./Substance:
0/Parathyroid Hormone; 0/Peptide Fragments; 7440-70-2/Calcium; EC 3.4.-/Peptide Hydrolases

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