Document Detail


Pararenal retroperitoneal Castleman's disease mimicking systemic lupus erythematosus.
MedLine Citation:
PMID:  20704605     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A 41-year-old man diagnosed initially as probable systemic lupus erythematosus (SLE) visited our hospital complaining of a persistent painful oral ulcer and multiple spots like coffee beans on his trunk. Antibodies except for anti-dsDNA and anti-histone antibodies and other serologies were negative. Conventional cytotoxic and immunomodulatory agents did not have any effect on these lesions. Computed tomography for evaluating persistent dry cough incidentally showed a huge mass in the left mid-retroperitoneum. Surgical treatment was done and the final diagnosis was Castleman's disease (CD). CD is a relatively rare disorder characterized by a massive non-malignant tumor of lymphoid tissues, with unknown etiology. It commonly presents as a localized soft tissue mass within the mediastinum or neck, and rarely in the retroperitoneal space. Since some cases of CD may share systemic, immune and histopathologic features of autoimmune disease, exact diagnosis is difficult to make based on the clinical and laboratory clues alone. We report herein an unusual case with pararenal retroperitoneal CD mimicking SLE.
Authors:
Ki-Jo Kim; Chul-Soo Cho; Jin-Jung Choi
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  International journal of rheumatic diseases     Volume:  13     ISSN:  1756-185X     ISO Abbreviation:  Int J Rheum Dis     Publication Date:  2010 Aug 
Date Detail:
Created Date:  2010-08-13     Completed Date:  2010-12-07     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101474930     Medline TA:  Int J Rheum Dis     Country:  England    
Other Details:
Languages:  eng     Pagination:  e20-5     Citation Subset:  IM    
Affiliation:
Division of Rheumatology, Department of Internal Medicine, Catholic University of Korea, St. Mary's Hospital, Seoul, Korea.
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MeSH Terms
Descriptor/Qualifier:
Adult
Biopsy
Diagnosis, Differential
Diagnostic Errors*
Giant Lymph Node Hyperplasia / diagnosis*,  immunology,  radiography,  surgery
Humans
Lupus Erythematosus, Systemic / diagnosis*,  immunology
Male
Retroperitoneal Space / radiography
Tomography, X-Ray Computed
Treatment Outcome

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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