| Paraquat-induced Fanconi syndrome. | |
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MedLine Citation:
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PMID: 16221089 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The ingestion of paraquat, a non-selective herbicide, can be fatal in humans. Paraquat is toxic to multiple organs, including the kidney, heart, gastrointestinal tract and central nervous system. Although paraquat has been established as one cause of acute tubular necrosis, Fanconi syndrome presenting as severe hypophosphataemia after paraquat intoxication has not been reported. Here, we report the case of a 44-year-old Korean woman who presented with generalized proximal tubular dysfunction including aminoaciduria, phosphaturia and glycosuria after paraquat intoxication. We found that severe hypophosphataemia induces deep drowsiness. Renal biopsy findings indicated the presence of acute tubular necrosis that may be reversible. |
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Authors:
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Hyo W Gil; Jong O Yang; Eun Y Lee; Sae Y Hong |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Nephrology (Carlton, Vic.) Volume: 10 ISSN: 1320-5358 ISO Abbreviation: Nephrology (Carlton) Publication Date: 2005 Oct |
Date Detail:
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Created Date: 2005-10-13 Completed Date: 2005-12-15 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9615568 Medline TA: Nephrology (Carlton) Country: Australia |
Other Details:
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Languages: eng Pagination: 430-2 Citation Subset: IM |
Affiliation:
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Department of Internal Medicine and Institute of Pesticide Poisoning, Soonchunhyang University Cheonan Hospital, Cheonan, Republic of Korea. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Biopsy Fanconi Syndrome / chemically induced*, pathology* Female Herbicides / poisoning* Humans Hypophosphatemia / chemically induced, pathology Kidney Tubular Necrosis, Acute / chemically induced, pathology Kidney Tubules, Proximal / drug effects, pathology Paraquat / poisoning* |
| Chemical | |
Reg. No./Substance:
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0/Herbicides; 4685-14-7/Paraquat |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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