Document Detail

Paraplegia treated with blood transfusion.
MedLine Citation:
PMID:  22824697     Owner:  NLM     Status:  In-Data-Review    
Extramedullary hematopoiesis is a compensatory response in patients with thalassemia and other chronic anemia and can result in compressive myelopathy, if untreated. Two young adults with history of thalassemia presented with symptoms of spinal cord compression. Presence of extramedullary hematopoiesis was confirmed by magnetic resonance imaging. Both the patients were treated with blood hypertransfusion and showed improvement clinically and radiologically. Although there are various options in the management of such condition, including decompression surgery and radiation treatment, hypertransfusion can be very effective even in severe compression of the spinal cord. Hypertransfusion should be tried as the first line of management in patients with thalassemia presenting with compressive myelopathy to decrease the bulk of extramedullary hematopoietic tissue.
Ajoy Sodani; Ashish Chawla; Amit Maheshwari; Mayoor Naigaonkar; Vinod Porwal
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Neurology India     Volume:  60     ISSN:  0028-3886     ISO Abbreviation:  Neurol India     Publication Date:    2012 May-Jun
Date Detail:
Created Date:  2012-07-24     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0042005     Medline TA:  Neurol India     Country:  India    
Other Details:
Languages:  eng     Pagination:  328-31     Citation Subset:  IM    
Department of Neurology, Sri Aurobindo Medical College and PG Institute, Indore, Madhya Pradesh, India.
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