Document Detail

Paraplegia as a complication of percutaneous vertebroplasty with polymethylmethacrylate: a case report.
MedLine Citation:
PMID:  12394938     Owner:  NLM     Status:  MEDLINE    
STUDY DESIGN: A case report and review of the literature are presented. OBJECTIVE: To present the first case of paraplegia as a complication of percutaneous vertebroplasty with polymethylmethacrylate in osteoporotic compression fracture. SUMMARY OF BACKGROUND DATA: Complications of percutaneous vertebroplasty with polymethylmethacrylate (PMMA) for the treatment of osteoporotic compression fracture were found to be rare and minor, except in two cases of major neurologic complication. METHODS: The reported case is that of a 66-year-old woman with multilevel vertebral osteopenia and compression fractures. Percutaneous vertebroplasty using polymethylmethacrylate was performed at three vertebral bodies (L2, L1, and T11) using careful techniques including venography, large cannula, proper preparation and amount of polymethylmethacrylate, and continuous visualization with fluoroscopy. RESULTS: Immediately after surgery, the patient had complete motor and sensory deficits at T11. Computed tomography scan showed spinal cord compression caused by venous leakage of polymethylmethacrylate. In anticipation of recovery from paraplegia, posterior decompression was performed from L2 to T10. CONCLUSIONS: Percutaneous vertebroplasty with polymethylmethacrylate is not as simple and risk free as advocated in the literature. Careful safeguards and modifications are needed for the procedure, and new and physiologic material could be substituted for polymethylmethacrylate.
Bong-Jin Lee; Sung-Rak Lee; Tae-Yeul Yoo
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Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  Spine     Volume:  27     ISSN:  1528-1159     ISO Abbreviation:  Spine     Publication Date:  2002 Oct 
Date Detail:
Created Date:  2002-10-23     Completed Date:  2002-11-29     Revised Date:  2009-07-09    
Medline Journal Info:
Nlm Unique ID:  7610646     Medline TA:  Spine (Phila Pa 1976)     Country:  United States    
Other Details:
Languages:  eng     Pagination:  E419-22     Citation Subset:  IM    
Department of Orthopaedic Surgery, Halla General Hospital, Jeju, South Korea.
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MeSH Terms
Decompression, Surgical
Drug Administration Routes
Lumbar Vertebrae / drug effects,  surgery
Osteoporosis / complications
Paraplegia / diagnosis*,  etiology*
Polymethyl Methacrylate / administration & dosage,  adverse effects*
Spinal Cord Compression / etiology*,  radiography
Spinal Fractures / etiology,  therapy
Thoracic Vertebrae* / drug effects,  surgery
Tomography, X-Ray Computed
Reg. No./Substance:
9011-14-7/Polymethyl Methacrylate

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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