Document Detail

Paraovarian cystic endosalpingiosis in association with tamoxifen therapy.
MedLine Citation:
PMID:  10767837     Owner:  NLM     Status:  MEDLINE    
This report describes a case of macroscopically visible cystic endosalpingiosis involving the paraovarian region in a woman who had been taking tamoxifen for breast cancer. A 2.5 cm multicystic lesion was seen on the external surface of the right ovary and histological examination showed a mass of dilated glands lined by ciliated tubal-type epithelium and set in a fibrovascular stroma. Cystic endosalpingiosis resulting in a tumour-like mass is a rarely described entity which is probably not well recognised by histopathologists. Although unlikely to be mistaken for malignancy, the lesion may result in diagnostic confusion. The role of tamoxifen in the development of the lesion in the present case is not clear but the oestrogenic effects of this drug may have contributed to its formation.
W G McCluggage; P E Weir
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of clinical pathology     Volume:  53     ISSN:  0021-9746     ISO Abbreviation:  J. Clin. Pathol.     Publication Date:  2000 Feb 
Date Detail:
Created Date:  2000-04-19     Completed Date:  2000-04-19     Revised Date:  2008-11-20    
Medline Journal Info:
Nlm Unique ID:  0376601     Medline TA:  J Clin Pathol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  161-2     Citation Subset:  AIM; IM    
Department of Pathology, Royal Group of Hospitals Trust, Belfast, Northern Ireland, UK.
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MeSH Terms
Antineoplastic Agents, Hormonal / adverse effects*
Cysts / chemically induced*,  pathology
Fallopian Tube Diseases / chemically induced*,  pathology
Middle Aged
Ovarian Cysts / chemically induced
Tamoxifen / adverse effects*
Reg. No./Substance:
0/Antineoplastic Agents, Hormonal; 10540-29-1/Tamoxifen

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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