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Paraneoplastic pemphigus (paraneoplastic autoimmune multiorgan syndrome): clinical presentations and pathogenesis.
MedLine Citation:
PMID:  21605807     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Paraneoplastic pemphigus is a rare condition with extremely high rates of mortality. Although its pathogenesis is incompletely understood, its pathologic findings have significant overlap with other autoimmune blistering diseases, such as pemphigus vulgaris, bullous pemphigoid, erythema multiforme and erosive lichen planus. A universally accepted consensus definition is needed to firmly define the condition. This would aid in identification of paraneoplastic pemphigus and the institution of timely and appropriate treatment to avoid rapid patient deterioration as well as recruitment for trials to further examine the pathogenesis and new therapeutic modalities. This article reviews the varied clinical presentations and pathologic characteristics pertaining to paraneoplastic pemphigus.
Authors:
John W Frew; Dédée F Murrell
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Dermatologic clinics     Volume:  29     ISSN:  1558-0520     ISO Abbreviation:  Dermatol Clin     Publication Date:  2011 Jul 
Date Detail:
Created Date:  2011-05-24     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8300886     Medline TA:  Dermatol Clin     Country:  United States    
Other Details:
Languages:  eng     Pagination:  419-25     Citation Subset:  IM    
Copyright Information:
Copyright © 2011 Elsevier Ltd. All rights reserved.
Affiliation:
Department of Dermatology, St George Hospital, Gray Street, Kogarah, Sydney, NSW, Australia; Faculty of Medicine, University of New South Wales, High Street, Kensington, Sydney, NSW, Australia.
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