| Paraneoplastic motor neuron disease associated with Purkinje cell autoantibody type 1. | |
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MedLine Citation:
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PMID: 20808163 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
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Motor neuron disease has been reported as a rare result of systemic cancers, likely related to an autoimmune effecter mechanism. These patients have been described as having a more rapid onset of symptoms than typical motor neuron disease. Few of these reports demonstrate an association of a cancer-related autoantibody and with motor neuron disease. We present a 54-year-old woman with infiltrating ductal carcinoma of the breast who later developed lower motor neuron disease and was found to have Purkinje cell autoantibodies type 1. The association of lower motor neuron disease as a consequence of breast cancer with this autoantibody profile has not been described previously. This report emphasizes the importance of considering a paraneoplastic syndrome in a patient with an uncommon presentation of motor neuron disease. |
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Authors:
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B Jane Distad; Michael D Weiss |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Journal of clinical neuromuscular disease Volume: 12 ISSN: 1537-1611 ISO Abbreviation: J Clin Neuromuscul Dis Publication Date: 2010 Sep |
Date Detail:
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Created Date: 2010-09-02 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 100887391 Medline TA: J Clin Neuromuscul Dis Country: United States |
Other Details:
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Languages: eng Pagination: 36-41 Citation Subset: IM |
Affiliation:
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Department of Neurology, University of Washington School Of Medicine, Seattle, WA, USA. jdistad@uw.edu |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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