Document Detail

Paraneoplastic limbic encephalitis, a complication of the testicular cancer.
MedLine Citation:
PMID:  11445490     Owner:  NLM     Status:  MEDLINE    
We report a case of paraneoplastic limbic encephalitis related to a testicular neoplasm. The syndrome is characterized by progressive amnesia and psychiatric disturbances resulting from an inflammatory reaction probably related to an immune response to the neuronal proteins expressed by tumors. It is usually associated with small cell lung cancer. In other cases, testicular cancer occurs more frequently than expected. Cranial magnetic resonance imaging may show increased signal intensity in the limbic cortex. Genitourinary examinations are sometimes inadequate. Testicular ultrasonography is recommended if no tumor is detected on the chest and abdominal computed tomography scan. The outcome of the treatment of the testicular cancer on the paraneoplastic syndrome is variable.
C Almeras; N Soussi; N Molko; A Azoulay-Cayla; F Richard; E J Chartier-Kastler
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Urology     Volume:  58     ISSN:  1527-9995     ISO Abbreviation:  Urology     Publication Date:  2001 Jul 
Date Detail:
Created Date:  2001-07-10     Completed Date:  2001-08-09     Revised Date:  2006-04-24    
Medline Journal Info:
Nlm Unique ID:  0366151     Medline TA:  Urology     Country:  United States    
Other Details:
Languages:  eng     Pagination:  105     Citation Subset:  IM    
Department of Urology, Pitie-Salpetriere Hospital, University Pierre et Marie Curie (Paris VI), Paris, France.
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MeSH Terms
Antineoplastic Combined Chemotherapy Protocols / therapeutic use
Chemotherapy, Adjuvant
Cisplatin / administration & dosage
Etoposide / administration & dosage
Limbic Encephalitis / diagnosis,  drug therapy,  etiology*
Middle Aged
Remission Induction
Seminoma / complications*,  diagnosis,  therapy
Teratoma / complications*,  diagnosis,  therapy
Testicular Neoplasms / complications*,  diagnosis*,  therapy
Reg. No./Substance:
15663-27-1/Cisplatin; 33419-42-0/Etoposide

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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