Document Detail


Paraneoplastic limbic encephalitis caused by ovarian teratoma with autoantibodies to glutamate receptor.
MedLine Citation:
PMID:  17603244     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We report a rare case of paraneoplastic limbic encephalitis with autoantibodies to glutamate receptor (GluR) in the cerebrospinal fluid (CSF). The 35-year-old woman with consciousness disturbance was diagnosed initially as non-herpetic encephalitis. Her signs and symptoms improved with acyclovir and steroid pulse therapy. However, after the treatment, an ovarian tumor was discovered, and we detected autoantibodies to GluR in the CSF. A possible association between the ovarian teratoma and GluR is suggested.
Authors:
Sadahisa Okamoto; Teruyuki Hirano; Yukitoshi Takahashi; Taro Yamashita; Eiichiro Uyama; Makoto Uchino
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Publication Detail:
Type:  Case Reports; Journal Article     Date:  2007-07-02
Journal Detail:
Title:  Internal medicine (Tokyo, Japan)     Volume:  46     ISSN:  1349-7235     ISO Abbreviation:  Intern. Med.     Publication Date:  2007  
Date Detail:
Created Date:  2007-07-02     Completed Date:  2007-08-23     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9204241     Medline TA:  Intern Med     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  1019-22     Citation Subset:  IM    
Affiliation:
Department of Neurology, Graduate School of Medical Sciences, Kumamoto University. s-okamoto@fc.kumamoto-u.ac.jp
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MeSH Terms
Descriptor/Qualifier:
Adult
Autoantibodies / analysis,  immunology*
Biopsy, Needle
Female
Follow-Up Studies
Humans
Immunohistochemistry
Japan
Limbic Encephalitis / etiology*,  immunology
Ovarian Neoplasms / complications*,  pathology,  surgery
Ovariectomy / methods
Rare Diseases
Receptors, Glutamate / immunology*
Risk Assessment
Teratoma / complications*,  pathology,  surgery
Treatment Outcome
Chemical
Reg. No./Substance:
0/Autoantibodies; 0/Receptors, Glutamate

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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