| Paraneoplastic intestinal pseudo-obstruction associated with high titres of Hu autoantibodies. | |
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MedLine Citation:
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PMID: 8291223 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Anti-Hu autoantibodies in high titres, as revealed with immunocytochemistry and Western blot, were present in a patient with gastrointestinal pseudo-obstruction and small-cell lung cancer (SCLC) bearing the Hu antigen. Marked neuron and nerve fibre loss were found in the myenteric plexus at postmortem. These findings show that neuronopathic Hu-associated gastrointestinal pseudo-obstruction can occur as the only paraneoplastic neurological symptom in patients with SCLC. |
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Authors:
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E Condom; A Vidal; R Rota; F Graus; J Dalmau; I Ferrer |
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Publication Detail:
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Type: Case Reports; Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Virchows Archiv. A, Pathological anatomy and histopathology Volume: 423 ISSN: 0174-7398 ISO Abbreviation: Virchows Arch A Pathol Anat Histopathol Publication Date: 1993 |
Date Detail:
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Created Date: 1994-02-22 Completed Date: 1994-02-22 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 8302198 Medline TA: Virchows Arch A Pathol Anat Histopathol Country: GERMANY |
Other Details:
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Languages: eng Pagination: 507-11 Citation Subset: IM |
Affiliation:
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Servicio Anatomía Patológica, Hospital Príncipes de España, Hospitalet de Llobregat, Spain. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Antibodies, Neoplasm
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analysis* Carcinoma, Small Cell / complications, immunology, pathology* Humans Intestinal Pseudo-Obstruction / etiology, immunology, pathology* Lung Neoplasms / complications, immunology, pathology* Male Middle Aged Paraneoplastic Syndromes / etiology, immunology, pathology* |
| Chemical | |
Reg. No./Substance:
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0/Antibodies, Neoplasm |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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