| Paraneoplastic gastro-intestinal anti-Hu syndrome in neuroblastoma. | |
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MedLine Citation:
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PMID: 18989884 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The anti-Hu syndrome is a well-known paraneoplastic syndrome and may be rarely seen in patients with neuroblastoma. However, it is relatively unknown that anti-Hu antibodies can cause gastro-intestinal signs and symptoms. We report on a child with neuroblastoma who presented with gastro-intestinal disturbances as a result of the anti-Hu syndrome and summaries two similar case reports reported in literature. Neuroblastoma patients with gastro-intestinal disturbances, ranging from constipation to a paralytic ileus, might suffer from the gastro-intestinal anti-Hu syndrome. The causative antibodies can be determined to diagnose or exclude this syndrome, and successful treatment is possible. |
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Authors:
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C A M Drukker; H A Heij; L C D Wijnaendts; J I M L Verbeke; G J L Kaspers |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Pediatric blood & cancer Volume: 52 ISSN: 1545-5017 ISO Abbreviation: Pediatr Blood Cancer Publication Date: 2009 Mar |
Date Detail:
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Created Date: 2009-01-15 Completed Date: 2009-01-30 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101186624 Medline TA: Pediatr Blood Cancer Country: United States |
Other Details:
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Languages: eng Pagination: 396-8 Citation Subset: IM |
Affiliation:
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Department of Pediatric Oncology/Hematology, VU University Medical Center, Amsterdam, The Netherlands. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Autoantibodies
/
analysis,
immunology* Child, Preschool Gastrointestinal Diseases / complications*, diagnosis*, immunology Hu Paraneoplastic Encephalomyelitis Antigens / immunology* Humans Male Neuroblastoma / complications*, diagnosis Paraneoplastic Syndromes / complications*, diagnosis*, immunology |
| Chemical | |
Reg. No./Substance:
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0/Autoantibodies; 0/Hu Paraneoplastic Encephalomyelitis Antigens |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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