| Paraneoplastic Cushing syndrome because of corticotrophin-releasing hormone-secreting Wilms' tumor. | |
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MedLine Citation:
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PMID: 18970948 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A 4-year-old boy with cushingoid appearance and a giant mass on his left kidney was referred to our department. Left nephroureterectomy was performed, and pathologic diagnosis was focal anaplastic nephroblastoma. Based on gradual decrease of postoperative weight, blood pressure, serum adrenocorticotropic hormone, and plasma cortisol levels, paraneoplastic Cushing syndrome because of Wilms' tumor was confirmed. Moreover, through immunohistochemical staining, we confirmed that the Wilms' tumor secreted corticotropin-releasing hormone and caused Cushing syndrome. |
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Authors:
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Jingfu Wang; Guangchao Zhang |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Journal of pediatric surgery Volume: 43 ISSN: 1531-5037 ISO Abbreviation: J. Pediatr. Surg. Publication Date: 2008 Nov |
Date Detail:
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Created Date: 2008-10-30 Completed Date: 2009-02-10 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0052631 Medline TA: J Pediatr Surg Country: United States |
Other Details:
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Languages: eng Pagination: 2099-101 Citation Subset: IM |
Affiliation:
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Department of Pediatric Oncology, Tianjin Cancer Hospital, Tianjin 300060, China. wangjingfu666@yahoo.com.cn |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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ACTH Syndrome, Ectopic
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etiology* Adrenocorticotropic Hormone / analysis, secretion* Antineoplastic Combined Chemotherapy Protocols / administration & dosage, therapeutic use Child, Preschool Combined Modality Therapy Cushing Syndrome / etiology* Dactinomycin / administration & dosage Doxorubicin / administration & dosage Humans Hydrocortisone / blood Immunoenzyme Techniques Kidney Neoplasms / complications, drug therapy, radiography, radiotherapy, secretion*, surgery Male Nephrectomy Remission Induction Tomography, X-Ray Computed Vincristine / administration & dosage Wilms Tumor / complications, drug therapy, radiography, radiotherapy, secretion*, surgery |
| Chemical | |
Reg. No./Substance:
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0/VAD regimen 2; 23214-92-8/Doxorubicin; 50-23-7/Hydrocortisone; 50-76-0/Dactinomycin; 57-22-7/Vincristine; 9002-60-2/Adrenocorticotropic Hormone |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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