Document Detail


Paranasal sinus fungus ball: diagnosis and management.
MedLine Citation:
PMID:  17944705     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Paranasal sinus fungus ball is an extramucosal mycosis, usually occurring in immunocompetent people as a monolateral lesion. To review the literature data and to report the Policlinico S. Matteo, University of Pavia experience, 81 patients presenting paranasal fungus ball have been treated (January 1994 to May 2005). Twenty-seven men and 54 women (19-91 years old; mean 49.4 years) were considered. Seventy-three patients had a single sinus affected, but eight presented multiple localisations. Maxillary was the most involved sinus followed by sphenoidal and ethmoidal. Moulds have been isolated in 28/81 cases. Histology showed fungal colonisation but not invasion in all cases. Tomography showed bone erosion in 33.3% of patients. All have been treated only by functional endoscopic sinus surgery. Seventy-seven of 81 patients have been cured. Four of 81 patients needed another surgical treatment. Follow up was between 6 and 132 months (average: 63 months). Fungus ball is a sinusal pathology caused by mycetes like Aspergillus spp. Histology confirms the fungal aethiology excluding tissue invasion. Mycological culture consented to identify the pathogenic mould in 34.5% of cases. Actually functional endoscopic sinus surgery is the gold standard for treatment of this pathology, and antifungal therapy is unnecessary.
Authors:
Fabio Pagella; Elina Matti; Francesca De Bernardi; Lucia Semino; Caterina Cavanna; Piero Marone; Claudio Farina; Paolo Castelnuovo
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Mycoses     Volume:  50     ISSN:  0933-7407     ISO Abbreviation:  Mycoses     Publication Date:  2007 Nov 
Date Detail:
Created Date:  2007-10-19     Completed Date:  2007-12-06     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8805008     Medline TA:  Mycoses     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  451-6     Citation Subset:  IM    
Affiliation:
Department of Otorhinolaryngology, IRCCS Policlinico San Matteo, University of Pavia, Pavia, Italy.
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Aged, 80 and over
Aspergillosis / diagnosis,  microbiology,  surgery
Aspergillus fumigatus / isolation & purification
Endoscopy*
Ethmoid Sinus / microbiology
Female
Fungi / classification,  isolation & purification*
Humans
Male
Maxillary Sinus / microbiology
Middle Aged
Mycoses* / diagnosis,  microbiology,  surgery
Paranasal Sinus Diseases* / diagnosis,  microbiology,  surgery
Sphenoid Sinus / microbiology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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