| Parameters of glycemic control and their relationship with zinc concentrations in blood and with superoxide dismutase enzyme activity in type 2 diabetes patients. | |
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MedLine Citation:
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PMID: 22231973 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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OBJECTIVE: This study assessed the relationship between the parameters of glycemic control, and zinc concentrations in blood and superoxide dismutase enzyme activity in type 2 diabetes patients. SUBJECTS AND METHODS: Seventy-three individuals, aged between 25 and 59 years, were divided into the experimental group (type 2 diabetes patients, n = 36) and control group (n = 37). Plasma and erythrocyte zinc concentrations, superoxide dismutase activity, and parameters of glycemic control were analyzed. RESULTS: Mean plasma zinc concentration was 74.1 ± 10.7 µg/dL and 68.8 ± 9.6 µg/dL, erythrocyte zinc concentration was 48.1 ± 9.5 µg/gHb and 41.2 ± 8.0 µg/gHb, and superoxide dismutase activity was 2248.9 ± 300.0 U/gHb and 2059.6 ± 285.4 U/gHb, in the experimental group and the control group, respectively (p < 0.05). CONCLUSION: Type 2 diabetes patients showed a positive response to oxidative stress due to adequate zinc concentration in blood and increased activity of superoxide dismutase, and the enzyme was influenced by serum insulin. |
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Authors:
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Vanessa Batista de Sousa Lima; Fabiane de Araújo Sampaio; Daila Leite Chaves Bezerra; José Machado Moita Neto; Dilina do Nascimento Marreiro |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Arquivos brasileiros de endocrinologia e metabologia Volume: 55 ISSN: 1677-9487 ISO Abbreviation: Arq Bras Endocrinol Metabol Publication Date: 2011 Dec |
Date Detail:
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Created Date: 2012-01-10 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0403437 Medline TA: Arq Bras Endocrinol Metabol Country: Brazil |
Other Details:
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Languages: eng Pagination: 701-7 Citation Subset: IM |
Affiliation:
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Department of Nutrition, Universidade Federal do Piauí, Teresina, PI, Brazil. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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