| Parameters of evaluation and correlation of renal phosphate handling and of parathyroid function in children. | |
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MedLine Citation:
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PMID: 2544818 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The aim of the study was to establish normal values for parameters of parathyroid (PT) function in childhood and to examine whether a correlation could be found between these parameters and tubular phosphate (P) reabsorption. Values for PTH (carboxyl terminal) and urinary cAMP (UcAMP) throughout childhood were found to be significantly lower than in adults, with mean values of 0.3 ng/ml (30 pmol/l) and 1.96 nmol/dl glomerular filtrate (GF) respectively. A significant correlation was found between UcAMP and tubular P reabsorption (TP), expressed by the equation: TP = 5.5-(0.5 x UcAMP) mg/dl GF (= 1.78-(0.16 x UcAMP) mmol/dl GF, with a scatter of 10.6 mg/dl around the mean (+/- 1 SD). These data appear to permit the evaluation of primary tubular components in patients with defects of renal P handling, as opposed to those related to PT activity. |
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Authors:
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H Stark; B Eisenstein; M Davidovits |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Nephron Volume: 51 ISSN: 0028-2766 ISO Abbreviation: Nephron Publication Date: 1989 |
Date Detail:
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Created Date: 1989-07-28 Completed Date: 1989-07-28 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0331777 Medline TA: Nephron Country: SWITZERLAND |
Other Details:
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Languages: eng Pagination: 478-81 Citation Subset: IM |
Affiliation:
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Pediatric Nephrology Unit, Beilinson, Medical Center, Petah Tiqva, Israel. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Absorption Adolescent Adult Child Child, Preschool Cyclic AMP / urine* Female Humans Infant Kidney Tubules / metabolism* Male Parathyroid Hormone / blood* Phosphates / metabolism* Reference Values |
| Chemical | |
Reg. No./Substance:
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0/Parathyroid Hormone; 0/Phosphates; 60-92-4/Cyclic AMP |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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