Document Detail

Paralytic ileus, a serious complication in acute diarrhoea disease among infants in developing countries.
MedLine Citation:
PMID:  2596276     Owner:  NLM     Status:  MEDLINE    
Intestinal hypomotility is a common late complication in infants with acute diarrhoeal disease in pakistan. Among the infants admitted to our gastrointestinal unit with a history of acute diarrhoea, 35% developed abdominal distension and 12% developed the full clinical picture of paralytic ileus. The infants with ileus were treated with decompression and total parenteral nutrition; in this group the mortality rate was 25%. We compared 30 infants who developed ileus (group A) with an age-matched control group of infants (group B) who were admitted because of acute diarrhoea but did not develope ileus. The use of antimotility drugs was significantly more frequent in group A. Serum-K was not different in in group A (3.92 +/- 0.22 mmol/l) and group B (4.32 +/- 0.18 mmol/1). However, there were more patients who had serum-K below 3 mmol/l in group A (8/30) than in group B (5/30). We conclude that the use of antimotility drugs predisposes to the development of ileus in infants with acute diarrhoea. Hypokalemia may contribute to ileus in a few cases but is generally not a prerequisite.
A Murtaza; S R Khan; K S Butt; Y Finkel; A Aperia
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Acta paediatrica Scandinavica     Volume:  78     ISSN:  0001-656X     ISO Abbreviation:  Acta Paediatr Scand     Publication Date:  1989 Sep 
Date Detail:
Created Date:  1990-01-25     Completed Date:  1990-01-25     Revised Date:  2009-11-11    
Medline Journal Info:
Nlm Unique ID:  0000211     Medline TA:  Acta Paediatr Scand     Country:  SWEDEN    
Other Details:
Languages:  eng     Pagination:  701-5     Citation Subset:  IM    
Department of Paediatrics, King Edward Medical College Lahore Pakistan.
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MeSH Terms
Acute Disease
Child, Preschool
Developing Countries*
Diarrhea / complications*
Diarrhea, Infantile / complications*
Infant, Newborn
Intestinal Obstruction / etiology*
Potassium / blood
Reg. No./Substance:

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