| Parallel supported synthesis of polyamine-imidazole conjugates. | |
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MedLine Citation:
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PMID: 15575667 Owner: NLM Status: PubMed-not-MEDLINE |
Abstract/OtherAbstract:
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[reaction: see text] A small collection of nine polyamine-imidazole conjugates, potentially acting as RNases A mimics, has been synthesized on SynPhase lanterns using amino alcohols and diamines as building blocks. Couplings were performed via S(N)2 alkylation of methanesulfonates with amines. The final introduction of N-4-nitrobenzyloxycarbonyldiamines allowed easy purification of the cleaved compounds. |
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Authors:
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Sylvie Picard; Myriam Le Roch; Jacques Renault; Philippe Uriac |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Organic letters Volume: 6 ISSN: 1523-7060 ISO Abbreviation: Org. Lett. Publication Date: 2004 Dec |
Date Detail:
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Created Date: 2004-12-03 Completed Date: 2005-05-17 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 100890393 Medline TA: Org Lett Country: United States |
Other Details:
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Languages: eng Pagination: 4711-4 Citation Subset: - |
Affiliation:
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Université Rennes 1, Institut de Chimie de Rennes, Synthèse et Extraction de Molécules à Visée Thérapeutique, Faculté des Sciences Biologiques et Médicales, 2 avenue du professeur Léon Bernard, 35043 Rennes, France. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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