| Parallel coil resonators for time-domain radiofrequency electron paramagnetic resonance imaging of biological objects. | |
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MedLine Citation:
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PMID: 10617448 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Resonators suitable for time-domain electron paramagnetic resonance spectroscopy and imaging at a radiofrequency capable of accommodating experimental animals such as mice are described. Design considerations included B(1) field homogeneity, optimal Q, spectral bandwidth, resonator ring-down, and sensitivity. Typically, a resonator with 25-mm diameter and 25-mm length was constructed by coupling 11 single loops in parallel with a separation of 2.5 mm. To minimize the resonator ring-down time and provide the necessary spectral bandwidth for in vivo imaging experiments, the Q was reduced predominantly by overcoupling. Capacitative coupling was utilized to minimize microphonic effects. The B(1) field in the resonator was mapped both radially and axially and found to be uniform and adequate for imaging studies. Imaging studies with phantom objects containing a narrow-line spin probe as well as in vivo objects administered with the spin probe show the suitability of these resonators for valid reproduction of the spin probe distribution in three dimensions. The fabrication of such resonators is simple and can be scaled up with relative ease to accommodate larger objects as well. |
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Authors:
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N Devasahayam; S Subramanian; R Murugesan; J A Cook; M Afeworki; R G Tschudin; J B Mitchell; M C Krishna |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Journal of magnetic resonance (San Diego, Calif. : 1997) Volume: 142 ISSN: 1090-7807 ISO Abbreviation: J. Magn. Reson. Publication Date: 2000 Jan |
Date Detail:
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Created Date: 2000-02-15 Completed Date: 2000-02-15 Revised Date: 2003-11-14 |
Medline Journal Info:
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Nlm Unique ID: 9707935 Medline TA: J Magn Reson Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 168-76 Citation Subset: IM |
Copyright Information:
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Copyright 2000 Academic Press. |
Affiliation:
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Division of Clinical Sciences, National Cancer Institute, Bethesda, Maryland 20892, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Electron Spin Resonance Spectroscopy / instrumentation*, methods Equipment Design Mice Mice, Inbred C3H Phantoms, Imaging Spin Labels |
| Chemical | |
Reg. No./Substance:
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0/Spin Labels |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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