Document Detail

Parallel Doppler assessment of yolk sac and intervillous circulation in normal pregnancy and missed abortion.
MedLine Citation:
PMID:  9859866     Owner:  NLM     Status:  MEDLINE    
This study assessed yolk sac morphology and vascularity and intervillous blood flow in normal early pregnancy and missed abortion. Transvaginal colour and pulsed Doppler were used in a prospective analysis of 87 normal pregnancies and 48 missed abortions between 6 and 12 weeks gestation. The Kruskal-Wallis rank test was used to calculate the difference in yolk sac diameter and vascularity visualization rate between gestational weeks. Repeated measures analysis of variance was used for comparison of the intervillous circulation between groups. The growth of the yolk sac was considered statistically significant between gestational weeks 6 and 9, being most prominent between 9 and 10 weeks of gestation. Vascularity of the yolk sac, characterized by low velocity and absence of diastolic flow, was demonstrated in 67 per cent of normal pregnancies. Yolk sac blood flow was detected in 19 per cent of the patients with missed abortion. Doppler analysis of the intervillous circulation demonstrated decreased peak velocity of the continuous flow in patients with missed abortion for gestational weeks 11 and 12. It is concluded that progressive decrease of yolk sac vascularity coincides with visualization of more prominent colour-coded areas within the intervillous space. In patients with missed abortion, such changes do not occur.
A Kurjak; S Kupesic
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Publication Detail:
Type:  Comment; Comparative Study; Journal Article    
Journal Detail:
Title:  Placenta     Volume:  19     ISSN:  0143-4004     ISO Abbreviation:  Placenta     Publication Date:  1998 Nov 
Date Detail:
Created Date:  1999-03-03     Completed Date:  1999-03-03     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8006349     Medline TA:  Placenta     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  619-23     Citation Subset:  IM    
Department of Obstetrics and Gynecology, Medical School University of Zagreb, Sveti Duh Hospital, Croatia.
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MeSH Terms
Abortion, Missed / physiopathology*,  ultrasonography
Blood Flow Velocity
Chorionic Villi / blood supply*,  ultrasonography
Pregnancy / physiology*
Pregnancy Trimester, First
Prospective Studies
Ultrasonography, Doppler, Color*
Ultrasonography, Prenatal*
Yolk Sac / blood supply*,  ultrasonography
Comment On:
Placenta. 1999 Sep;20(7):609-11   [PMID:  10452916 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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