| Paragangliomas in an endemic area: from genetics to morphofunctional imaging. A pictorial essay. | |
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MedLine Citation:
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PMID: 22020432 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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The aim of this pictorial essay is to illustrate the morphological [computed tomography (CT) and magnetic resonance imaging (MRI)], vascular (angiography) and functional (nuclear medicine) features of paragangliomas, uncommon lesions of the head and neck region and even more of the thorax, abdomen and pelvis, arising in an endemic area in northern Italy. These hypervascular, well-circumscribed masses usually have innocuous clinical manifestations as slowly enlarging soft-tissue lesions; however, more rarely, they can cause cranialnerve palsy, particularly lesions arising near the skull base, or symptoms related to their secreting activity. Most paragangliomas are benign and their prognosis is directly related to the location of the tumour: those arising at the carotid body have the best outcome, whereas those located at the skull base have a less favourable prognosis. Angiography is required preoperatively in larger paragangliomas for surgical planning (vascular mapping) and, rarely, for preoperative embolisation. Morphological and functional imaging is also mandatory for surgical and/or radiometabolic treatment planning and follow-up. |
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Authors:
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G Casagranda; S Demattè; D Donner; S Sammartano; U Rozzanigo; P Peterlongo; M Centonze |
Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-10-21 |
Journal Detail:
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Title: La Radiologia medica Volume: - ISSN: 1826-6983 ISO Abbreviation: - Publication Date: 2011 Oct |
Date Detail:
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Created Date: 2011-10-24 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0177625 Medline TA: Radiol Med Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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Dipartimento di Radiodiagnostica, APSS di Trento, L.go Medaglie d'Oro 10, 38100, Trento, Italy, giulia.casagranda@apss.tn.it. |
Vernacular Title:
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I paragangliomi in una zona endemica: dalla genetica all'imaging morfo-funzionale. Rassegna iconografica. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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