| Paragangliomas of the head and neck: diagnosis and treatment. | |
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MedLine Citation:
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PMID: 15883711 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Paragangliomas of the head and neck (HNP) represent rare tumors of neural crest origin. They are highly vascular neoplasms that are benign in the majority of cases. The site of origin defines the name given those tumors. In the head and neck, they most commonly occur at the carotid bifurcation, where they are referred to as carotid body tumors (CBT). Other common sites of origin are the jugular bulb (jugular paraganglioma; JP), the tympanic plexus on the promontory (tympanic paraganglioma; TP) and the vagal nerve (vagal paraganglioma; VP). Patients with cervical paragangliomas frequently present with a painless, slowly enlarging mass in the lateral neck. In many patients with TP and JP, tinnitus and hearing loss are early symptoms. JP patients often suffer from lower cranial nerve deficits. Evaluation by an imaging modality is necessary to establish the diagnosis. Imaging procedures frequently used include B-mode sonography with color-coded Doppler sonography, computed tomography (CT), magnetic resonance imaging (MRI) and digital substraction angiography (DSA). Debate exists in the literature regarding the different treatment modalities for paragangliomas which include surgery, radiotherapy and stereotactic radiosurgery. The role of preoperative angiography and embolization has also been a matter of discussion. The diagnostic work up and the different treatment options for patients with head and neck paragangliomas will be presented and discussed. |
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Authors:
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C C Boedeker; G J Ridder; J Schipper |
Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Familial cancer Volume: 4 ISSN: 1389-9600 ISO Abbreviation: Fam. Cancer Publication Date: 2005 |
Date Detail:
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Created Date: 2005-05-10 Completed Date: 2005-09-13 Revised Date: 2009-11-03 |
Medline Journal Info:
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Nlm Unique ID: 100898211 Medline TA: Fam Cancer Country: Netherlands |
Other Details:
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Languages: eng Pagination: 55-9 Citation Subset: IM |
Affiliation:
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Department of Otorhinolaryngology -- Head and Neck Surgery, University of Freiburg, Killianstrasse 5, 79106 Freiburg, Germany. boedeker@hno.ukl.uni-freiburg.de |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Angiography, Digital Subtraction Embolization, Therapeutic Head and Neck Neoplasms / complications, diagnosis*, surgery* Humans Magnetic Resonance Imaging Paraganglioma / complications, diagnosis*, surgery* Radiosurgery / methods Tomography, X-Ray Computed Ultrasonography, Doppler |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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