Document Detail

Paraganglioma of the vagina: the first report of a rare tumor in a child.
MedLine Citation:
PMID:  9842649     Owner:  NLM     Status:  MEDLINE    
Paraganglioma (extra-adrenal pheochromocytoma) is a rare tumor, particularly in childhood. Those in the female genital tract are exceptionally rare, with only 9 cases reported in detail since 1926. All were seen in adults and only two arose in the vagina. This study examined the incidence of this tumor in the childhood population of the West Midlands region of the United Kingdom since 1957 and found 4 cases: 2 abdominal, 1 para-aortic, and 1 carotid body. A recent additional case is reported in the vagina of a child aged 11 years, who presented with heavy vaginal bleeding in the absence of hypertension. Initial diagnosis suggested rhabdomyosarcoma and near complete excision was carried out. Since this is the first such case to be described in a child, the outcome can only be assumed. Although histopathological examination suggested the benign nature of the tumor, implying that surgical excision was sufficient treatment, close follow-up is recommended.
S E Parkes; F Raafat; B J Morland
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Publication Detail:
Type:  Case Reports; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Pediatric hematology and oncology     Volume:  15     ISSN:  0888-0018     ISO Abbreviation:  Pediatr Hematol Oncol     Publication Date:    1998 Nov-Dec
Date Detail:
Created Date:  1999-02-16     Completed Date:  1999-02-16     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8700164     Medline TA:  Pediatr Hematol Oncol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  545-51     Citation Subset:  IM    
West Midlands Regional Children's Tumour Research Group, Birmingham Children's Hospital NHS Trust, UK.
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MeSH Terms
Child, Preschool
Diagnosis, Differential
Paraganglioma* / diagnosis,  pathology,  physiopathology,  surgery
Rhabdomyosarcoma / diagnosis
Vaginal Neoplasms* / diagnosis,  pathology,  physiopathology,  surgery

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