Document Detail

Paraganglioma of the cauda equina. A case report and review of the literature.
MedLine Citation:
PMID:  8611199     Owner:  NLM     Status:  MEDLINE    
A 59-year-old man presented with clinical evidence of a primary tumor of the cauda equina region. It was well circumscribed and was completely removed by neurosurgery. Routine staining showed that it had structural similarities to an ependymoma, but immunohistochemistry with antisera to synaptophysin, NSE, chromogranin-A and PGP 9.5 proved it to be a neuroendocrine tumor, i.e. a paraganglioma. We propose the use of endocrine markers in cases with tumors of the cauda equina to differentiate a paraganglioma from an ependymoma. Paragangliomas appear to have a better clinical outcome than ependymomas. Recurrence after surgery for a paraganglioma in the cauda equina region, especially if it is encapsulated, is rarely encountered.
J Bak; Y Olsson; L Grimelius; B Spännare
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Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  APMIS : acta pathologica, microbiologica, et immunologica Scandinavica     Volume:  104     ISSN:  0903-4641     ISO Abbreviation:  APMIS     Publication Date:  1996 Mar 
Date Detail:
Created Date:  1996-05-31     Completed Date:  1996-05-31     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  8803400     Medline TA:  APMIS     Country:  DENMARK    
Other Details:
Languages:  eng     Pagination:  234-40     Citation Subset:  IM    
Department of Pathology, University Hospital, Uppsala, Sweden.
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MeSH Terms
Cauda Equina* / surgery
Diagnosis, Differential
Ependymoma / diagnosis
Middle Aged
Neoplasm Proteins / analysis
Paraganglioma* / chemistry,  diagnosis,  pathology,  surgery
Peripheral Nervous System Neoplasms* / chemistry,  diagnosis,  pathology,  surgery
Tumor Markers, Biological / analysis
Reg. No./Substance:
0/Neoplasm Proteins; 0/Tumor Markers, Biological

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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