Document Detail

Paradoxical cerebral embolism as the initial symptom in a patient with ovarian cancer.
MedLine Citation:
PMID:  17689401     Owner:  NLM     Status:  MEDLINE    
This report concerns a 37-year-old patient with ovarian cancer and a paradoxical cerebral embolism as the initial symptom. She developed acute onset of left quadrantic hemianopia during coughing. Brain magnetic resonance imaging showed an acute multiple infarction, and a simultaneous acute pulmonary embolism was observed. Transesophageal echocardiography showed a patent foramen ovale, multidetector row computed tomography an ovarian tumor and infarction of the spleen, whereas multidetector row computed tomography venography showed right iliac vein compression by the ovarian tumor. The diagnosis was stage Ic ovarian cancer. Because blood stasis of the pelvic vein is a major risk factor for venous thrombosis, the presence of a patent foramen ovale should alert physicians to examine not only veins in the lower extremities but also the pelvic and intra-abdominal veins as a source paradoxical embolism.
Yuko Wada; Ryuichi Takahashi; Chie Yanagihara; Yo Nishimura
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association     Volume:  16     ISSN:  1532-8511     ISO Abbreviation:  J Stroke Cerebrovasc Dis     Publication Date:    2007 Mar-Apr
Date Detail:
Created Date:  2007-08-10     Completed Date:  2007-09-14     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9111633     Medline TA:  J Stroke Cerebrovasc Dis     Country:  United States    
Other Details:
Languages:  eng     Pagination:  88-90     Citation Subset:  IM    
Department of Neurology, Nishi-Kobe Medical Center, Hyogo, Japan.
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MeSH Terms
Constriction, Pathologic
Cystadenocarcinoma, Serous / complications,  diagnosis*,  radiography
Embolism, Paradoxical / etiology*
Heart Septal Defects, Atrial / complications*
Hemianopsia / etiology
Iliac Vein / pathology,  radiography
Magnetic Resonance Imaging
Ovarian Neoplasms / complications,  diagnosis*,  radiography
Paraneoplastic Syndromes / etiology*
Pulmonary Embolism / complications
Splenic Infarction / complications,  radiography
Thrombophilia / etiology*
Tomography, Spiral Computed

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