| Paradoxical Interictal Cerebral Cortical Hypermetabolism on Brain FDG PET in Sturge-Weber Syndrome. | |
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MedLine Citation:
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PMID: 21368611 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Sturge-Weber syndrome (SWS) is a congenital, noninherited neurocutaneous syndrome, characterized by angiomas located in the facial skin and leptomeninges and often associated with severe epilepsy. We report a paradoxical finding on FDG PET with interictally increased metabolism in the affected hemisphere and contralateral cerebellum in an infant with epilepsy due to SWS. PET imaging was performed to assess the extent and degree of cerebral metabolic impairment before epilepsy surgery. Although the exact mechanism underlying this paradoxical hypermetabolism remains unclear, it may play an important role in the pathophysiologic progression of SWS. |
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Authors:
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Mohamad Al-Makhzomi; Karolien Goffin; Liesbeth De Waele; Lieven Lagae; Koen Van Laere |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Clinical nuclear medicine Volume: 36 ISSN: 1536-0229 ISO Abbreviation: Clin Nucl Med Publication Date: 2011 Apr |
Date Detail:
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Created Date: 2011-03-03 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 7611109 Medline TA: Clin Nucl Med Country: United States |
Other Details:
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Languages: eng Pagination: 313-4 Citation Subset: IM |
Affiliation:
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From the *Division of Nuclear Medicine, University Hospital Leuven, Leuven, Belgium; and †Department of Pediatrics, University Hospital Leuven, Leuven, Belgium. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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