| Paradoxical development of a sarcoid-like reaction during successful chemotherapy for seminoma. | |
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MedLine Citation:
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PMID: 20647660 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
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Although the association between seminoma and sarcoidosis or a sarcoid-like reaction has been well recognized, a paradoxical case during chemotherapy for seminoma has not been reported. We report the first case of a sarcoid-like reaction that developed paradoxically during successful chemotherapy for recurrent seminoma. A 36-year-old Japanese man had recurrent seminoma in abdominal lymph nodes four years after left orchiectomy. Chemotherapy consisting of bleomycin, etoposide and cisplatin had reduced the abdominal mass, but mediastinal and bilateral hilar lymphadenopathy newly appeared. Surgical biopsy of the mediastinal lymph nodes and left nephrectomy and retroperitoneal lymphadenectomy revealed noncaseating granulomas only in mediastinal lymph nodes and confirmed complete remission of seminoma. Nine months later the thoracic lymphadenopathy had resolved spontaneously. |
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Authors:
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Kiminobu Tanizawa; Eisaku Tanaka; Seishu Hashimoto; Satoshi Noma; Yoichiro Kobashi; Kazuhiro Okumura; Toru Shindo; Yoshio Taguchi |
Publication Detail:
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Type: Case Reports; Journal Article Date: 2010-07-15 |
Journal Detail:
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Title: Internal medicine (Tokyo, Japan) Volume: 49 ISSN: 1349-7235 ISO Abbreviation: Intern. Med. Publication Date: 2010 |
Date Detail:
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Created Date: 2010-07-21 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9204241 Medline TA: Intern Med Country: Japan |
Other Details:
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Languages: eng Pagination: 1423-6 Citation Subset: IM |
Affiliation:
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Department of Respiratory Medicine, Tenri Hospital, Tenri, Japan. tanizawa@kuhp.kyoto-u.ac.jp |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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