Document Detail

Paracoccidioidomycosis: case report and review.
MedLine Citation:
PMID:  8922797     Owner:  NLM     Status:  MEDLINE    
A previously well 59-year-old man presented with paracoccidioidomycosis, more than 15 years after leaving South America. He failed to respond to conventional therapies, first with oral itraconazole and then with amphotericin B plus sulfadiazine, and eventually died of recurrent arterial emboli possibly due to paracoccidioidomycotic aortitis. This patient's presentation demonstrates the difficulties that may be encountered in diagnosing and managing this disease. Paracoccidioidomycosis should be suspected in patients with an appropriate travel history who experience weight loss and have pulmonary, mucosal, and cutaneous lesions. This article comprehensively reviews the literature, with emphasis on epidemiology, clinical presentation, diagnosis, and therapy with imidazole antifungal medications.
B J Manns; B W Baylis; S J Urbanski; A P Gibb; H R Rabin
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Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America     Volume:  23     ISSN:  1058-4838     ISO Abbreviation:  Clin. Infect. Dis.     Publication Date:  1996 Nov 
Date Detail:
Created Date:  1997-02-28     Completed Date:  1997-02-28     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  9203213     Medline TA:  Clin Infect Dis     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1026-32     Citation Subset:  IM    
Department of Internal Medicine, Foothills Medical Center, Alberta, Canada.
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MeSH Terms
Amphotericin B / therapeutic use
Fatal Outcome
Itraconazole / therapeutic use
Middle Aged
Paracoccidioides / isolation & purification*
Paracoccidioidomycosis* / drug therapy,  pathology,  physiopathology
Sulfadiazine / therapeutic use
Treatment Failure
Reg. No./Substance:
1397-89-3/Amphotericin B; 68-35-9/Sulfadiazine; 84625-61-6/Itraconazole

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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