Document Detail

Parachordoma of the buttock: an immunohistochemical case study and review.
MedLine Citation:
PMID:  7530308     Owner:  NLM     Status:  MEDLINE    
We report a case of parachordoma occurring in the buttock of a 43-year-old man, and review 20 cases of parachordoma reported in the English literature. The tumor in our case was grossly 3 cm in dimension, solid, lobulated and grayish-white in color. Microscopically, the tumor consisted of epithelioid and spindle cells, and fibromyxoid stroma. The epithelioid cells were immunohistochemically positive for vimentin, S-100 protein, neuron-specific enolase, keratin, carcinoembryonic antigen and epithelial membrane antigen, and negative for HMB45. These findings are similar to those for chordoma rather than extraskeletal myxoid chrondrosarcoma. Although the etiopathogenesis of parachordoma remains obscure, Schwann cells or some other neuron-related cell origin are suspected.
M Hirokawa; T Manabe; K Sugihara
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Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  Japanese journal of clinical oncology     Volume:  24     ISSN:  0368-2811     ISO Abbreviation:  Jpn. J. Clin. Oncol.     Publication Date:  1994 Dec 
Date Detail:
Created Date:  1995-02-17     Completed Date:  1995-02-17     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0313225     Medline TA:  Jpn J Clin Oncol     Country:  JAPAN    
Other Details:
Languages:  eng     Pagination:  336-9     Citation Subset:  IM    
Department of Pathology, Kawasaki Medical School, Okayama.
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MeSH Terms
Carcinoembryonic Antigen / metabolism
Chondrosarcoma / pathology
Chordoma / chemistry,  pathology*
Diagnosis, Differential
Keratins / metabolism
S100 Proteins / metabolism
Soft Tissue Neoplasms / chemistry,  pathology*
Reg. No./Substance:
0/Carcinoembryonic Antigen; 0/S100 Proteins; 68238-35-7/Keratins

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