Document Detail

Parabens: a real hazard or a scare story?
MedLine Citation:
PMID:  23131320     Owner:  NLM     Status:  Publisher    
Parabens belong to a family of preservatives that are widely used, particularly in the cosmetic, pharmaceutical and food industries. Four esters are commonly used: methyl, ethyl, propyl and butyl parabens. They are either used alone or, for better efficacy, in the form of a mixture. They have been the target of a media smear campaign since 2005. Several studies have failed to formally prove their alleged responsibility in the occurrence of breast cancer. At recommended concentrations, methyl and ethyl parabens have no hormonal effect in humans. Propyl and butyl parabens are still being investigated as regards their effects on fertility in men exposed during early childhood. Parabens are well-known for having weak sensitising properties and for their absence of toxicity whereas new substitution products, not as well-known, may lead to new cases of contact allergy.
Florence Castelain; Michel Castelain
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-11-7
Journal Detail:
Title:  European journal of dermatology : EJD     Volume:  -     ISSN:  1952-4013     ISO Abbreviation:  Eur J Dermatol     Publication Date:  2012 Nov 
Date Detail:
Created Date:  2012-11-7     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9206420     Medline TA:  Eur J Dermatol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Department of Dermatology, St Jacques Hospital, 25000 Besançon, France.
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