| Paraaortic lymph node metastasis in patients with intra-abdominal malignancies: CT vs PET. | |
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MedLine Citation:
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PMID: 19764096 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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AIM: To compare the diagnostic accuracy of computed tomography (CT) and positron emission tomography (PET) for the preoperative detection of paraaortic lymph node (PAN) metastasis in patients with intra-abdominal malignancies. METHODS: Sixty-six patients with intra-abdominal malignancies who underwent both CT and PET before lymphadenectomy were included in this study. Histopathologically, 13 patients had metastatic PAN, while 53 had non-metastatic PAN. The CT criteria for metastasis were: short diameter of > 8 mm, lobular or irregular shape, and/or combined ancillary findings, including necrosis, conglomeration, vessel encasement, and infiltration. The PET criterion was positive fluorodeoxyglucose (FDG) uptake. The sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and accuracy of both modalities were compared with the pathologic findings, and the false positive and false negative cases with both CT and PET were analyzed. RESULTS: The sensitivity, specificity, PPV, NPV, and accuracy of CT were 61.5%, 84.9%, 50%, 90% and 80.3%, respectively. For PET, the percentages were 46.2%, 100%, 100%, 88.3%, and 89.4%. Additionally, there were 8 false positive CT cases (8/53, 15.1%) and zero false positive PET cases. Of the 13 metastatic PANs, there were 5 false negative CT scans (38.5%) and 7 (53.9%) false negative PET scans. CONCLUSION: For detecting PAN metastasis, CT is more sensitive than PET, while PET is more specific. |
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Authors:
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Mi-Jung Lee; Mi Jin Yun; Mi-Suk Park; Seung Hwan Cha; Myeong-Jin Kim; Jong Doo Lee; Ki Whang Kim |
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Publication Detail:
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Type: Comparative Study; Journal Article |
Journal Detail:
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Title: World journal of gastroenterology : WJG Volume: 15 ISSN: 1007-9327 ISO Abbreviation: World J. Gastroenterol. Publication Date: 2009 Sep |
Date Detail:
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Created Date: 2009-09-18 Completed Date: 2010-02-02 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 100883448 Medline TA: World J Gastroenterol Country: China |
Other Details:
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Languages: eng Pagination: 4434-8 Citation Subset: IM |
Affiliation:
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Department of Diagnostic Radiology and Research Institute of Radiological Science, Yonsei University College of Medicine, Seodaemun-Gu, Seoul 120-752, South Korea. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Abdominal Neoplasms
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diagnosis*,
secondary Adult Aged Aorta / radionuclide imaging False Negative Reactions False Positive Reactions Female Fluorodeoxyglucose F18 / diagnostic use Humans Image Processing, Computer-Assisted Lymphatic Metastasis / radiography*, radionuclide imaging* Male Middle Aged Positron-Emission Tomography / methods* Predictive Value of Tests Radiopharmaceuticals / diagnostic use Reproducibility of Results Retrospective Studies Sensitivity and Specificity Sentinel Lymph Node Biopsy Tomography, X-Ray Computed / methods* |
| Chemical | |
Reg. No./Substance:
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0/Radiopharmaceuticals; 63503-12-8/Fluorodeoxyglucose F18 |
| Comments/Corrections | |
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