Document Detail

Papuloerythroderma 2009: two new cases and systematic review of the worldwide literature 25 years after its identification by Ofuji et al.
MedLine Citation:
PMID:  20339287     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Even after the description of papuloerythroderma of Ofuji (PEO) in 1984, little is known about this clinical entity. OBJECTIVE: To report on 2 new cases of PEO and review of the worldwide literature on this topic. METHODS: Article citations were searched on several biomedical search engines (PubMed, EMBASE, SCOPUS, Google Scholar). Papers were retrieved either online or in print. RESULTS: A grand total of 170 PEO cases were identified. Most patients were older than 55 years and of Asian or white descent, with an overall male/female ratio of 4.0. Itch and the deck-chair sign were observed in all patients. Peripheral eosinophilia, lymphocytopenia and increased serum IgE were common findings. Histopathology mostly showed aspecific inflammation, while 17 showed histological features of cutaneous T-cell lymphoma (CTCL). Atopy, malignancies, infections and drugs were rarely linked to PEO. CONCLUSION: PEO represents a rather monomorphous entity both clinically and, with the remarkable exception of CTCL, also histologically. Nonetheless, no causative factor could be identified in the vast majority of cases. An etiological classification and diagnostic criteria are proposed in the attempt to contribute framing this puzzling clinical entity.
Daniele Torchia; Maria Miteva; Shasa Hu; Carlos Cohen; Paolo Romanelli
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Publication Detail:
Type:  Case Reports; Journal Article; Review     Date:  2010-03-26
Journal Detail:
Title:  Dermatology (Basel, Switzerland)     Volume:  220     ISSN:  1421-9832     ISO Abbreviation:  Dermatology (Basel)     Publication Date:  2010  
Date Detail:
Created Date:  2010-06-30     Completed Date:  2010-10-14     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9203244     Medline TA:  Dermatology     Country:  Switzerland    
Other Details:
Languages:  eng     Pagination:  311-20     Citation Subset:  IM    
Copyright Information:
Copyright (c) 2010 S. Karger AG, Basel.
Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, 1444 N.W. 9th Avenue, Miami, FL 33136, USA.
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MeSH Terms
Aged, 80 and over
Furosemide / administration & dosage
Hydroxyzine / therapeutic use
Hypercholesterolemia / drug therapy
Hypertension / drug therapy
Middle Aged
Simvastatin / therapeutic use
Skin Diseases, Papulosquamous / diagnosis*,  drug therapy,  etiology*,  pathology
Triamcinolone / therapeutic use
Reg. No./Substance:
124-94-7/Triamcinolone; 54-31-9/Furosemide; 68-88-2/Hydroxyzine; 79902-63-9/Simvastatin

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