Document Detail


Papillary thyroid cancer incidence rates vary significantly by birthplace in Asian American women.
MedLine Citation:
PMID:  21207130     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: To investigate how birthplace influences the incidence of papillary thyroid cancer among Asian American women.
METHODS: Birthplace- and ethnic-specific age-adjusted and age-specific incidence rates were calculated using data from the California Cancer Registry for the period 1988-2004. Birthplace was statistically imputed for 30% of cases using a validated imputation method based on age at Social Security number issuance. Population estimates were obtained from the US Census. Incidence rate ratios (IRR) and 95% confidence intervals (CI) were estimated for foreign-born vs. US-born women.
RESULTS: Age-adjusted incidence rates of papillary thyroid cancer among Filipina (13.7 per 100,000) and Vietnamese (12.7) women were more than double those of Japanese women (6.2). US-born Chinese (IRR = 0.48, 95% CI: 0.40-0.59) and Filipina women (IRR = 0.74, 95% CI: 0.58-0.96) had significantly higher rates than those who were foreign-born; the opposite was observed for Japanese women (IRR = 1.55, 95% CI: 1.17-2.08). The age-specific patterns among all foreign-born Asian women and US-born Japanese women showed a slow steady increase in incidence until age 70. However, among US-born Asian women (except Japanese), substantially elevated incidence rates during the reproductive and menopausal years were evident.
CONCLUSIONS: Ethnic- and birthplace-variation in papillary thyroid cancer incidence can provide insight into the etiology of this increasingly common and understudied cancer.
Authors:
Pamela L Horn-Ross; Laura A McClure; Ellen T Chang; Christina A Clarke; Theresa H M Keegan; Rudolph P Rull; Thu Quach; Scarlett Lin Gomez
Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't     Date:  2011-01-05
Journal Detail:
Title:  Cancer causes & control : CCC     Volume:  22     ISSN:  1573-7225     ISO Abbreviation:  Cancer Causes Control     Publication Date:  2011 Mar 
Date Detail:
Created Date:  2011-02-21     Completed Date:  2011-06-02     Revised Date:  2012-09-18    
Medline Journal Info:
Nlm Unique ID:  9100846     Medline TA:  Cancer Causes Control     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  479-85     Citation Subset:  IM    
Affiliation:
Cancer Prevention Institute of California, 2201 Walnut Ave., Suite 300, Fremont, CA 94538, USA. pam@cpic.org
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Asian Americans*
California
China / ethnology
Ethnic Groups*
Female
Humans
Incidence
Japan / ethnology
Middle Aged
Philippines / ethnology
Thyroid Neoplasms* / epidemiology,  ethnology
United States / epidemiology
Vietnam / ethnology
Grant Support
ID/Acronym/Agency:
N01-PC-35136/PC/NCI NIH HHS; N01-PC-35139/PC/NCI NIH HHS; N01PC35136/CA/NCI NIH HHS; N01PC35139/CA/NCI NIH HHS; N02-PC-15105/PC/NCI NIH HHS; U55/CCR921930-02//PHS HHS
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