Document Detail


Papaverine testing of impotent patients following nerve-sparing radical prostatectomy.
MedLine Citation:
PMID:  3352039     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
To investigate the etiology of impotence following nerve-sparing radical retropubic prostatectomy we performed papaverine testing on 23 patients who did not regain erections sufficient for vaginal penetration. Intervals from surgery to testing ranged from 3 to 30 months, with an average of 9 months. All patients achieved some degree of tumescence. In response to intracavernous papaverine injection only 1 patient (5 per cent) obtained an erection equivalent to the preoperative state. Of 18 patients who were fully potent preoperatively 8 (44 per cent) achieved an erection less than normal but judged to be sufficient for intercourse by the examining physician. Twelve patients, including 2 who were not fully potent preoperatively, had erections of poor quality insufficient for vaginal penetration. The results suggest that in most of these patients postoperative erectile dysfunction is predominantly vasculogenic in origin. Thus, factors other than injury to the neurovascular bundles may be responsible for postoperative impotence.
Authors:
R R Bahnson; W J Catalona
Related Documents :
9232279 - Skin replacement by cultured keratinocyte grafts: an australian experience.
9278659 - Outcome and predictors of success of biofeedback for constipation.
17968979 - Randomized clinical trial of moxonidine in patients undergoing major vascular surgery.
7272679 - Perforation of the oesophagus: experience in a general hospital.
10594509 - Value of a surgical high-dependency unit.
9611029 - Long-term outcome of lumbar discectomy in children and adolescents sixteen years of age...
21636229 - A cupulolith repositioning maneuver in the treatment of horizontal canal cupulolithiasis.
18269529 - Assessment of progestin-only therapy for endometriosis in macaque.
20980119 - Management of childhood intussusception after reduction by enema.
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  The Journal of urology     Volume:  139     ISSN:  0022-5347     ISO Abbreviation:  J. Urol.     Publication Date:  1988 Apr 
Date Detail:
Created Date:  1988-04-29     Completed Date:  1988-04-29     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0376374     Medline TA:  J Urol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  773-4     Citation Subset:  AIM; IM    
Affiliation:
Division of Urologic Surgery, Washington University School of Medicine, St. Louis, Missouri.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Erectile Dysfunction / etiology*
Humans
Male
Papaverine / diagnostic use*
Penile Erection / drug effects*
Postoperative Complications / etiology
Prostatectomy / adverse effects*
Time Factors
Chemical
Reg. No./Substance:
58-74-2/Papaverine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Familial double testicular tumors: identical chromosome changes in seminoma and embryonal carcinoma ...
Next Document:  Pharmacological treatment of erectile dysfunction after radical prostatectomy.