Document Detail

The Pap smear for detection of bacterial vaginosis.
MedLine Citation:
PMID:  17466304     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To assess validity of Pap smears in diagnosing bacterial vaginosis. METHOD: A prospective diagnostic accuracy study with 533 women in Mombasa, Kenya. Diagnosis of bacterial vaginosis using clinical observations scored with simplified Amsel's criteria and Bethesda system for Pap smears was compared with a reference standard (Nugent criteria for gram stains). Both laboratory tests were interpreted blindly. RESULT: Bacterial vaginosis prevalence was 36.7% (191/521) with Nugent criteria. Pap smear sensitivity and specificity were 59.4% (111/187) and 83.3% (270/324), with corresponding figures for simplified Amsel's criteria of 44.8% (81/181) and 84.8% (263/310). For Pap smear and simplified Amsel's criteria, positive predictive values were 67.3 and 63.3%, and negative predictive values 78.0% and 72.5%. CONCLUSION: In diagnosing bacterial vaginosis, Pap smears have moderate sensitivity (though higher than simplified Amsel's criteria). Specificity of Pap smears is adequate. Including bacterial vaginosis assessment as a standard component of Pap smears warrants consideration.
A Karani; H De Vuyst; S Luchters; J Othigo; K Mandaliya; M F Chersich; M Temmerman
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Publication Detail:
Type:  Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't     Date:  2007-04-26
Journal Detail:
Title:  International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics     Volume:  98     ISSN:  0020-7292     ISO Abbreviation:  Int J Gynaecol Obstet     Publication Date:  2007 Jul 
Date Detail:
Created Date:  2007-06-18     Completed Date:  2007-10-04     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0210174     Medline TA:  Int J Gynaecol Obstet     Country:  Ireland    
Other Details:
Languages:  eng     Pagination:  20-3     Citation Subset:  IM    
International Centre for Reproductive Health, Mombasa, Kenya.
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MeSH Terms
Gentian Violet
Kenya / epidemiology
Prospective Studies
Reference Standards
Sensitivity and Specificity
Vaginal Smears / methods*
Vaginosis, Bacterial / diagnosis*,  epidemiology
Reg. No./Substance:
0/Gram's stain; 0/Phenazines; 548-62-9/Gentian Violet

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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