Document Detail

Pantoea agglomerans bloodstream infection in preterm neonates.
MedLine Citation:
PMID:  18836282     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To report an uncommon incidence of sporadic bloodstream infection (BSI) caused by Pantoea agglomerans in preterm neonates.
CASE PRESENTATION AND INTERVENTION: Fives cases of nosocomial BSI with P. agglomerans in preterm neonates (weight <or=1,500 g; age 8-17 days; gestational age 26-30 weeks) are presented. All cases were late onset neonatal sepsis (>7 days of age). Lethargy, skin mottling and bradycardia were often present. Although there was no evidence of pneumonia, desaturation was a common feature. Thrombocytopenia developed in 4 patients, metabolic acidosis in 2 and jaundice in 2. No bleeding tendency or disseminating intravascular coagulation was recorded. Organisms cultured from blood were identified by the Vitek-2 system (bioMérieux, France) and the findings confirmed by testing the isolate on the API 20E system. All isolates shared in vitro susceptibility to gentamicin, amikacin, ciprofloxacin, piperacillin/tazobactam and meropenem. One patient was treated with a cefotaxime/amikacin combination, 2 with meropenem and the remaining 2 with tazocin. All patients responded well to antibiotic treatment and survived.
CONCLUSION: P. agglomerans is an unusual pathogen in the etiology of neonatal sepsis. Despite significant clinical deterioration, early detection and proper antibiotic therapy carry a favorable outcome.
Nasser Yehia A Aly; Hadeel N Salmeen; Reda A Abo Lila; Prem A Nagaraja
Publication Detail:
Type:  Case Reports; Journal Article     Date:  2008-10-03
Journal Detail:
Title:  Medical principles and practice : international journal of the Kuwait University, Health Science Centre     Volume:  17     ISSN:  1423-0151     ISO Abbreviation:  Med Princ Pract     Publication Date:  2008  
Date Detail:
Created Date:  2008-10-06     Completed Date:  2009-02-06     Revised Date:  2012-09-10    
Medline Journal Info:
Nlm Unique ID:  8901334     Medline TA:  Med Princ Pract     Country:  Switzerland    
Other Details:
Languages:  eng     Pagination:  500-3     Citation Subset:  IM    
Copyright Information:
(c) 2008 S. Karger AG, Basel.
Department of Tropical Medicine and Hygiene, Faculty of Medicine, University of Alexandria, Alexandria, Egypt.
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MeSH Terms
Anti-Bacterial Agents / therapeutic use
Bacteremia / drug therapy,  microbiology*
Cross Infection / drug therapy,  microbiology
Infant, Newborn
Infant, Premature
Infant, Premature, Diseases / drug therapy,  microbiology*
Respiration, Artificial
Reg. No./Substance:
0/Anti-Bacterial Agents

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