Document Detail

Pannus overgrowth after mitral valve replacement with a Carpentier-Edwards pericardial bioprosthesis.
MedLine Citation:
PMID:  19330506     Owner:  NLM     Status:  MEDLINE    
A Carpentier-Edwards pericardial (CEP) bioprosthesis was explanted from an 81-year-old woman due to nonstructural dysfunction 9 years after mitral valve replacement. The nonstructural dysfunction produced severe regurgitation in the mitral position. During the surgery, excessive pannus overgrowth was seen on the left ventricular side of the CEP bioprosthesis. Pannus overgrowth was prominent on one leaflet. That leaflet was stiff and shortened due to the excessive overgrowth of pannus. In this patient, the distortion of one leaflet was the main reason for transvalvular leakage of the CEP bioprosthesis in the mitral position. A new CEP bioprosthesis was implanted in the mitral position. Pathological analysis revealed fibrotic pannus with a small amount of cellular material over the leaflets of the resected CEP valve. This change was marked on the distorted leaflet.
Takeshi Oda; Seiya Kato; Eiki Tayama; Shuji Fukunaga; Hidetoshi Akashi; Shigeaki Aoyagi
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Publication Detail:
Type:  Case Reports; Journal Article     Date:  2009-03-29
Journal Detail:
Title:  Journal of artificial organs : the official journal of the Japanese Society for Artificial Organs     Volume:  12     ISSN:  1619-0904     ISO Abbreviation:  J Artif Organs     Publication Date:  2009  
Date Detail:
Created Date:  2009-03-30     Completed Date:  2009-07-17     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9815648     Medline TA:  J Artif Organs     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  55-7     Citation Subset:  IM    
Department of Cardiovascular Surgery, Kurume University School of Medicine, Fukuoka, Japan.
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MeSH Terms
Aged, 80 and over
Heart Failure / etiology*,  pathology
Heart Valve Prosthesis / adverse effects*
Heart Valve Prosthesis Implantation*
Mitral Valve / pathology*

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