Document Detail


Panniculitis due to non-tuberculous mycobacteria in two immunocompromised patients.
MedLine Citation:
PMID:  15844639     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Inflammation of subcutaneous tissue (panniculitis) may occur in association with tuberculosis, but so far only three cases of non-tuberculous mycobacteria-related lobular panniculitis have been reported. We describe two new cases with marked cellular immunity failure due to hypercorticism. Clinical presentation did not differ significantly from lobular panniculitis of other aetiologies. Histological samples displayed signs of lobular panniculitis and clues for mycobacteria infection with granulomatous lesions and presence of numerous acid-fast bacilli on special staining. Both patients responded quickly to a combination of macrolides, ethambutol and fluoroquinolones. However, like in other infections with tuberculous or non-tuberculous mycobacteria, long-term treatment (at least 6 months) was necessary to prevent relapses.
Authors:
Anne-Marie Mohty; Olivier Dereure; Didier Bessis; Luc Durand; Jean-Jacques Guilhou
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Acta dermato-venereologica     Volume:  84     ISSN:  0001-5555     ISO Abbreviation:  Acta Derm. Venereol.     Publication Date:  2004  
Date Detail:
Created Date:  2005-04-22     Completed Date:  2005-06-09     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0370310     Medline TA:  Acta Derm Venereol     Country:  Norway    
Other Details:
Languages:  eng     Pagination:  469-71     Citation Subset:  IM    
Affiliation:
Department of Dermatology, University Hospital of Montpellier, France.
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MeSH Terms
Descriptor/Qualifier:
Aged
Anti-Bacterial Agents / therapeutic use
Female
Humans
Immunocompromised Host*
Male
Middle Aged
Mycobacterium Infections, Atypical / diagnosis*,  drug therapy
Panniculitis / microbiology*
Chemical
Reg. No./Substance:
0/Anti-Bacterial Agents

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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