| The Paneth cell in the adenoma of familial polyposis coli. | |
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MedLine Citation:
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PMID: 1064485 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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It is said that the Paneth cells are found in the large intestine in a pathological state such as ulcerative colitis or adenoma. We examined the Paneth cells in the adenomas of familial polyposis coli. Nine cases including one case of Gardner's syndrome comprised the material for the examination of the Paneth cells because the caecum was available for the examination. The remaining one case had no Paneth cells. In two cases, the Paneth cells were found among the adenomas in the areas beyond the caecum and the proximal part of the colon ascendens. In one remarkable case, the Paneth cells were found in 43% of the adenomas in the caecum. Seven cases were carcinomas but no Paneth cells were found in or near the carcinoma. In the control cases, which were taken from the resected colon with a disease other than familial polyposis coli, the Paneth cells were found confined to the caecum. We concluded that the distribution of the Paneth cell-bearing adenomas reflects the distribution of the Paneth cells in the normal mucosa of the large intestine and that the Paneth cells in the adenoma may have differentiated in the adenoma. |
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Authors:
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T Iwama; J Utsunomiya; E Hamaguchi |
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Publication Detail:
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Type: Comparative Study; Journal Article |
Journal Detail:
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Title: The Bulletin of Tokyo Medical and Dental University Volume: 22 ISSN: 0040-8921 ISO Abbreviation: Bull. Tokyo Med. Dent. Univ. Publication Date: 1975 Jun |
Date Detail:
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Created Date: 1976-09-02 Completed Date: 1976-09-02 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0405503 Medline TA: Bull Tokyo Med Dent Univ Country: JAPAN |
Other Details:
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Languages: eng Pagination: 151-4 Citation Subset: D; IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adenoma
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pathology* Adult Aged Colonic Neoplasms / pathology* Epithelial Cells Epithelium / pathology Female Humans Intestinal Mucosa Intestinal Polyps / pathology* Intestine, Large / cytology Male Middle Aged Rectal Neoplasms / pathology* |
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