| Pancytopenia with severe thrombocytopenia in a patient treated with twice-weekly LDL-apheresis by polyacrylate adsorption from whole blood. | |
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MedLine Citation:
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PMID: 20101676 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Pancytopenia with severe thrombocytopenia occurred in a patient treated with low-density lipoprotein (LDL)-apheresis by polyacrylate adsorption from whole blood, after treatment frequency had been increased from once to twice a week. Cell counts recovered with discontinuation of LDL-apheresis, but thrombocytopenia recurred after resumption of twice-weekly treatments. Thrombocyte counts remained stable following the replacement of polyacrylate adsorption from whole blood by double-filtration plasmapheresis. The complications' close coincidence with twice-weekly polyacrylate adsorption from whole blood suggests a causal relationship, although by a still unknown mechanism. Monitoring of thrombocytes should be advised in patients treated with LDL-apheresis by polyacrylate adsorption from whole blood. |
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Authors:
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Rainer Nowack; Günther Wiedemann |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Journal of clinical apheresis Volume: 25 ISSN: 1098-1101 ISO Abbreviation: J Clin Apher Publication Date: 2010 |
Date Detail:
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Created Date: 2010-04-14 Completed Date: 2010-07-12 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8216305 Medline TA: J Clin Apher Country: United States |
Other Details:
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Languages: eng Pagination: 77-80 Citation Subset: IM |
Affiliation:
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Nephrology/Dialysis Centre Lindau, Friedrichshafener Str. 82, Lindau D-88131, Germany. nowack@dialyse-lindau.de |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Acrylic Resins
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chemistry* Adsorption Adult Blood Component Removal / methods* Cholesterol, LDL / blood, isolation & purification* Filtration Humans Hyperlipoproteinemia Type II / therapy Male Pancytopenia / therapy* Plasmapheresis Thrombocytopenia / therapy* |
| Chemical | |
Reg. No./Substance:
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0/Acrylic Resins; 0/Cholesterol, LDL; 9003-01-4/carbopol 940 |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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