| Pancreatitis in pregnancy. | |
| | |
MedLine Citation:
|
PMID: 18978108 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
OBJECTIVE: To estimate the incidence, cause, and complications of pancreatitis in pregnancy and to identify factors associated with adverse outcomes. METHODS: This study was a chart review of all pregnant patients diagnosed with pancreatitis from 1992-2001 at 15 participating hospitals. Information was collected on presentation, management, and outcome, along with the number of deliveries at each hospital. RESULTS: During the 10 years of the study, 101 cases of pancreatitis occurred among 305,101 deliveries, yielding an incidence of one in 3,021 (.03%). There were no maternal deaths; perinatal mortality was 3.6%. Eighty-nine women had acute pancreatitis, and 12 women had chronic pancreatitis. The majority (66%) of cases of acute pancreatitis were biliary in origin, and they were associated with better outcomes than nonbiliary causes. Cases of gallstone pancreatitis that received surgical or endoscopic intervention during pregnancy had lower rates of preterm delivery and recurrence than those that were conservatively managed, but this difference was not significant (P=.2). Alcohol was responsible for 12.3% of acute pancreatitis cases and 58% of chronic pancreatitis cases and was associated with increased rates of recurrence and preterm delivery. A calcium level, triglycerides, or both was not obtained in half of cases identified as idiopathic. CONCLUSION: Pancreatitis is a rare event in pregnancy, occurring in approximately 3 in 10,000 pregnancies. Although it is most often acute and related to gallstones, nonbiliary causes should be sought because they are associated with worse outcomes. LEVEL OF EVIDENCE: III. |
| | |
Authors:
|
Jennifer J Eddy; Mark D Gideonsen; Jonathan Y Song; William A Grobman; Peggy O'Halloran |
Related Documents
:
|
3607598 - Keratoconus with spontaneous perforation of the cornea. 8018608 - Transient diabetes insipidus and acute fatty liver of pregnancy. 1419458 - Life-threatening acute respiratory distress in late pregnancy. 8408828 - In utero acute graft-versus-host disease in a neonate with severe combined immunodefici... 9316128 - Risks for fetal abnormalities after very and moderately elevated af-afps. 3607598 - Keratoconus with spontaneous perforation of the cornea. |
Publication Detail:
|
Type: Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't |
Journal Detail:
|
Title: Obstetrics and gynecology Volume: 112 ISSN: 0029-7844 ISO Abbreviation: Obstet Gynecol Publication Date: 2008 Nov |
Date Detail:
|
Created Date: 2008-11-03 Completed Date: 2008-12-24 Revised Date: 2011-01-25 |
Medline Journal Info:
|
Nlm Unique ID: 0401101 Medline TA: Obstet Gynecol Country: United States |
Other Details:
|
Languages: eng Pagination: 1075-81 Citation Subset: AIM; IM |
Affiliation:
|
University of Wisconsin School of Medicine and Public Health, Department of Family Medicine, Eau Claire, Wisconsin 54703, USA. jjemdg@sbcgolbal.net |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Female Gallstones / complications, epidemiology Humans Illinois / epidemiology Incidence Infant, Newborn Pancreatitis / complications*, epidemiology Perinatal Mortality* Pregnancy Pregnancy Complications* / epidemiology Premature Birth / epidemiology*, etiology Retrospective Studies Wisconsin / epidemiology |
| Grant Support | |
ID/Acronym/Agency:
|
UL1 RR025011-01/RR/NCRR NIH HHS; UL1 RR025011-02/RR/NCRR NIH HHS; UL1 RR025011-03/RR/NCRR NIH HHS |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Acupuncture to induce labor: a randomized controlled trial.
Next Document: First-trimester maternal serum a disintegrin and metalloprotease 12 (ADAM12) and adverse pregnancy o...