| Pancreaticobiliary maljunction: etiologic concepts based on radiologic aspects. | |
| | |
MedLine Citation:
|
PMID: 11323587 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
BACKGROUND: The purpose of this study was to develop a new concept of the embryonic etiology of pancreaticobiliary maljunction (PBM) based on cholangiopancreatograms. METHODS: The subjects were 202 patients with PBM (60 men and 142 women) in whom the junction of the pancreatic and bile ducts was radiologically diagnosed as being located outside of the duodenal wall; 133 of the 202 patients also had congenital cystic dilatation of the bile duct (CCBD). RESULTS: The length of the duct from the junction to the orifice of the major papilla (the common channel) ranged from 0.5 to 5 cm on the cholangiopancreatograms. Small radicles of the pancreatic duct arose from the common channel in 36 of the 202 patients. This finding suggests that the common channel is itself the main pancreatic duct in patients with PBM. Moreover, cholangiopancreatography revealed that in 99 of the 202 patients, there was a narrowed duct segment distal to the biliary cyst in patients with CCBD or distal to the normal bile duct in those without CCBD; the length of the narrowed segment varied. Histologic examination revealed smaller branches that had arisen from this narrowed segment in 2 anatomic specimens. This also suggests that the narrowed ductal segment belongs to the pancreatic duct system. CONCLUSION: PBM is an anomaly that is probably caused by a disturbance in the embryologic connections (misarrangement) of the pancreatic and biliary duct system that occurs extremely early during gestation when the bile duct joins with the ventral pancreatic duct system. PBM is not due to an arrest of the normal migration of the common channel into the duodenal lumen during embryonic development. |
| | |
Authors:
|
Y Matsumoto; H Fujii; J Itakura; M Mogaki; M Matsuda; A Morozumi; M A Fujino; K Suda |
Related Documents
:
|
551137 - Surgery of coexisting biliary malformations in choledochal cyst. 6781327 - The liver in rocky mountain spotted fever. 17401237 - Double-barrel common bile duct: a rare cause of extrahepatic biliary obstruction. 1306647 - Does the type of anomalous arrangement of pancreaticobiliary ducts influence the surger... 18944707 - Virtual lesion extension: a measure to quantify the effects of bacterial blight on rice... 7796017 - Choledochal cysts in adults. |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Gastrointestinal endoscopy Volume: 53 ISSN: 0016-5107 ISO Abbreviation: Gastrointest. Endosc. Publication Date: 2001 May |
Date Detail:
|
Created Date: 2001-04-27 Completed Date: 2001-08-09 Revised Date: 2004-11-17 |
Medline Journal Info:
|
Nlm Unique ID: 0010505 Medline TA: Gastrointest Endosc Country: United States |
Other Details:
|
Languages: eng Pagination: 614-9 Citation Subset: IM |
Affiliation:
|
First Department of Surgery, Yamanashi Medical University, Tamaho, Japan. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adult Aged Cholangiopancreatography, Endoscopic Retrograde Common Bile Duct / abnormalities* Female Humans Male Middle Aged Pancreatic Ducts / abnormalities*, radiography |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Self-expanding metal esophageal stent with anti-reflux mechanism.
Next Document: Prospective evaluation of complications in outpatient GI endoscopy: a survey among German gastroente...