Document Detail


Pancreatic secretory responses to intravenous hyperalimentation and intraduodenal elemental and full liquid diets.
MedLine Citation:
PMID:  6431126     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Intravenous hyperalimentation and enteral elemental diets have both been advocated for the nutritional support of patients with acute pancreatitis, pancreatic fistula, and proximal small bowel fistula. The exocrine pancreatic responses to these nutrients compared to one another and to full liquid diet have been inadequately studied. Therefore, pancreatic protein, volume, and bicarbonate responses to graded doses of (1) intravenous hyperalimentation, (2) intraduodenal elemental diet, and (3) intraduodenal full liquid diet were compared in duplicate experiments in five dogs with chronic pancreatic fistulas. Both intraduodenal elemental and full liquid diets caused comparable and significant dose-related increases in pancreatic protein, volume, and bicarbonate outputs over basal levels (p less than 0.05). In contrast, there was no stimulation of pancreatic secretion by intravenous hyperalimentation. It therefore appears that of the methods studied, only intravenous hyperalimentation can provide full nutritional support while maintaining the pancreas at rest.
Authors:
B E Stabile; M Borzatta; R S Stubbs
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, Non-P.H.S.    
Journal Detail:
Title:  JPEN. Journal of parenteral and enteral nutrition     Volume:  8     ISSN:  0148-6071     ISO Abbreviation:  JPEN J Parenter Enteral Nutr     Publication Date:    1984 Jul-Aug
Date Detail:
Created Date:  1984-09-14     Completed Date:  1984-09-14     Revised Date:  2007-02-21    
Medline Journal Info:
Nlm Unique ID:  7804134     Medline TA:  JPEN J Parenter Enteral Nutr     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  377-80     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Animals
Bicarbonates / secretion
Dogs
Enteral Nutrition*
Food, Formulated*
Pancreas / secretion*
Pancreatic Fistula / etiology,  metabolism,  therapy*
Parenteral Nutrition*
Parenteral Nutrition, Total*
Proteins / secretion
Chemical
Reg. No./Substance:
0/Bicarbonates; 0/Proteins

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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