Document Detail

Pancreatic primary lymphoma: a case report and review of the literature.
MedLine Citation:
PMID:  16286277     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Primary pancreatic lymphoma is a rare but treatable malignancy (less than 1% of pancreatic tumors) that may be clinically confused with pancreatic adenocarcinoma. METHODS: In a patient with upper abdominal pain, ultrasonography and CT detected a mass in pancreatic head, which compressed the common bile duct. The patient received a Whipple's operation and intraoperative frozen sections of the mass showed an anaplastic carcinoma. Immunohistochemical staining was used to indicate the origin and prognosis of tumor. RESULTS: Grossly the tumor involved the pancreatic head, soft in consistence and invaded part of the gastric wall. Histologically, the tumor was composed mainly of large and moderate neoplastic cells, which were diffusely positive for CD20 and Bcl-6 antigens, indicating the features of diffusely large B cell lymphoma. CONCLUSIONS: The proper diagnosis of the tumor should be made with CD20 and Bcl-6 immunohistochemical study. Radical surgery is indicated for resectable carcinoma but not for a chemosensitive lymphoma.
Yuan Ji; Tian-Tao Kuang; Yun-Shan Tan; Ying Chen; Hai-Ying Zeng; Da-Yong Jin
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Publication Detail:
Type:  Case Reports; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Hepatobiliary & pancreatic diseases international : HBPD INT     Volume:  4     ISSN:  1499-3872     ISO Abbreviation:  HBPD INT     Publication Date:  2005 Nov 
Date Detail:
Created Date:  2005-11-15     Completed Date:  2006-01-26     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  101151457     Medline TA:  Hepatobiliary Pancreat Dis Int     Country:  China    
Other Details:
Languages:  eng     Pagination:  622-6     Citation Subset:  IM    
Department of Pathology, Zhongshan Hospital, Fudan University, Shanghai 200032, China.
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MeSH Terms
Diagnosis, Differential
Lymphoma / pathology,  radiography,  surgery*
Middle Aged
Pancreatic Neoplasms / pathology,  radiography,  surgery*

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