Document Detail

Pancreatic polypeptide hyperplasia causing watery diarrhea syndrome: a case report.
MedLine Citation:
PMID:  10071589     Owner:  NLM     Status:  MEDLINE    
Neuroendocrine tumours of the pancreas can secrete numerous peptides, leading to various recognizable clinical syndromes. The secretion of pancreatic polypeptide has been used as a marker for neuroendocrine tumours but is considered to be a biologically inert peptide. A 37-year-old woman had watery diarrhea syndrome from pancreatic polypeptide hyperplasia. Only 2 other reported cases in the literature have described pancreatic polypeptide hyperplasia; however, this is the first reported case in which the patient was successfully treated by surgical resection, with a 2-year follow-up. This report and review of the literature illustrate that pancreatic polypeptide hypersecretion may present as a clinical endocrinopathy.
J L Pasieka; N Hershfield
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Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  Canadian journal of surgery. Journal canadien de chirurgie     Volume:  42     ISSN:  0008-428X     ISO Abbreviation:  Can J Surg     Publication Date:  1999 Feb 
Date Detail:
Created Date:  1999-03-25     Completed Date:  1999-03-25     Revised Date:  2013-11-01    
Medline Journal Info:
Nlm Unique ID:  0372715     Medline TA:  Can J Surg     Country:  CANADA    
Other Details:
Languages:  eng     Pagination:  55-8     Citation Subset:  IM    
Department of Surgery, University of Calgary.
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MeSH Terms
Diagnosis, Differential
Islets of Langerhans / pathology*
Pancreatic Neoplasms / diagnosis,  pathology,  surgery*
Pancreatic Polypeptide / blood*
Vipoma / diagnosis,  pathology,  surgery*
Reg. No./Substance:
59763-91-6/Pancreatic Polypeptide

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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